28291-75-0

Basic information

• Product Name: N-Cyclohexylbenzothiazole-2-amine
• Synonyms: N-Cyclohexyl-2-benzothiazolamine;N-Cyclohexylbenzothiazole-2-amine
• CAS NO: 28291-75-0
• Molecular Formula: C₁₃H₁₆N₂S
• Molecular Weight: 232.34
• Mol File: 28291-75-0.mol
• Article Data: 24

Chemical Properties

• Melting Point: 107 °C
• Boiling Point: 368.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.234±0.06 g/cm3(Predicted)
• PKA: 3.44±0.10(Predicted)
• CAS DataBase Reference: N-Cyclohexylbenzothiazole-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cyclohexylbenzothiazole-2-amine(28291-75-0)
• EPA Substance Registry System: N-Cyclohexylbenzothiazole-2-amine(28291-75-0)

Safety Data

• Hazardous Substances Data: 28291-75-0(Hazardous Substances Data)

Usage

General Description

N-Cyclohexylbenzothiazole-2-amine, also known as CBS, is a chemical compound commonly used as an accelerator in the production of rubber and latex. It belongs to the family of benzothiazole derivatives and is known for its ability to promote the vulcanization process, which improves the elasticity, strength, and durability of rubber products. CBS is a white to light-yellow powder with a mild odor, and it is soluble in a variety of organic solvents. However, it is considered a hazardous substance and has been classified as a potential carcinogen. Therefore, proper handling and safety precautions are necessary when working with this chemical.

Upstream product

• 1418139-86-2 C₁₃H₁₅IN₂ 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 108-91-8 cyclohexylamine 
• 931-53-3 Cyclohexyl isocyanide 
• 137-07-5 2-amino-benzenethiol 
• 98041-44-2 2-iodophenyl isothiocyanate 
• 250122-02-2 C₁₃H₁₇IN₂S 
• 615-43-0 2-iodophenylamine 
• 1122-82-3 isothiocyanatocyclohexane 
• 4426-69-1 cyclohexyl isoselenocyanate 
• 250122-00-0 C₁₃H₁₇BrN₂S 
• 722-03-2 N-cyclohexyl-N'-phenylthiourea 

Downstream Products

• 120-78-5 di(benzothiazol-2-yl)disulfide 
• 108-91-8 cyclohexylamine 
• 137267-11-9 1-{2-[(Z)-Cyclohexylimino]-benzothiazol-3-yl}-3-phenoxy-propan-2-ol 

Relevant articles and documents

Molecular iodine-mediated synthesis of thiocarbamates from thiols, isocyanides and water under metal-free conditions

A simple and practical molecular iodine-mediated method for the efficient construction of thiocarbamates from isocyanides, thiols and water under metal-free and mild conditions has been developed. A variety of thiocarbamates were easily synthesized through this methodology, which has the advantages of simple operation, eco-friendly conditions, good functional group tolerance, and readily accessible raw materials.

A practical synthesis of 2-aminobenzothiazoles via copper(I)-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates in ionic liquids

A copper(I)-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates was achieved in hydrophobic [bmim][PF6] ionic liquid under mild conditions, generating a variety of 2-aminobenzothiazoles in good to excellent yields. The tandem reaction that was carried out in [bmim][PF6] has some obvious advantages such as accelerated reaction rate and increased yield as compared with the reaction run in volatile solvents such as toluene. Furthermore, the CuI/1,10-phenanthroline catalytic system can be reused up to eight times without loss of activity and efficiency.

Water-Mediated Synthesis of Benzazole and Thiourea Motifs by Reacting Naturally Occurring Isothiocyanate with Amines

An efficient, green, and facile method has been developed for the synthesis of benzazole and thiourea analogues from naturally occurring erucin in moderate to good yields. The reaction was carried out in water without using any metal catalyst or base. The present method tolerated the various functional groups on aromatic rings and also applicable for other isothiocyanates.