283153-64-0

Basic information

• Product Name: methyl 3-(4-(hydroxymethyl)phenyl)propanoate
• Synonyms: methyl 3-(4-(hydroxymethyl)phenyl)propanoate
• CAS NO: 283153-64-0
• Molecular Weight: 194.23
• Mol File: 283153-64-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 3-(4-(hydroxymethyl)phenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(4-(hydroxymethyl)phenyl)propanoate(283153-64-0)
• EPA Substance Registry System: methyl 3-(4-(hydroxymethyl)phenyl)propanoate(283153-64-0)

Safety Data

• Hazardous Substances Data: 283153-64-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 23359-08-2 4-formylcinnamic acid 
• 115974-97-5 methyl (E)-4-carboxyl cinnamate 
• 619-66-9 4-Carboxybenzaldehyde 
• 7560-50-1 methyl (2E)-3-(4-formylphenyl)acrylate 
• 141286-90-0 methyl (E)-3-(4-(hydroxymethyl)phenyl)acrylate 

Downstream Products

• 56703-34-5 3-[4-(hydroxymethyl)phenyl]propanoic acid 
• 1426441-01-1 methyl 3-(4-((benzyl(5-hydroxypentyl)carbamoyloxy)methyl)phenyl)propanoate 
• 1018674-58-2 cyclopentyl 4-(4-{3-[(1-isobutoxyethoxy)amino]-3-oxopropyl}benzyl)piperazine-2-carboxylate 
• 1426441-02-2 methyl 3-(4-((benzyl(5-O-(tetrahydropyranyloxy)pentyl)carbamoyloxy)methyl)phenyl)propanoate 
• 71924-53-3 methyl 3-(4-formyl-phenyl)propanoate 

Relevant articles and documents

Reduction of Electron-Deficient Alkenes Enabled by a Photoinduced Hydrogen Atom Transfer

Direct hydrogen atom transfer from a photoredox-generated Hantzsch ester radical cation to electron-deficient alkenes has enabled the development of an efficient formal hydrogenation under mild, operationally simple conditions. The HAT-driven mechanism is supported by experimental and computational studies. The reaction is applied to a variety of cinnamate derivatives and related structures, irrespective of the presence of electron-donating or electron-withdrawing substituents in the aromatic ring and with good functional group compatibility. (Figure presented.).

HDAC INHIBITORS

Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independently represent =C- or =N-; W is a divalent radical -CH=CH- or CH2CH2-; R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intracellular carboxyesterase enzymes to a carboxylic acid group; R2 is the side chain of a natural or non-natural alpha amino acid; z is 0 or 1; and Y, L1, and X1 are as defined in the claims.