28317-12-6Relevant articles and documents
Proton and Carbon-13 Nuclear Magnetic Resonance Spectrometry of Formaldehyde in Water
Botlan, D. J. Le,Mechin, B. G.,Martin, G. J.
, p. 587 - 591 (1983)
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Carbon-13 NMR Study of Reaction of Aqueous Formaldehyde with Amine Salts: Evidences for Reductive Methylation by Intramolecular Hydride Transfer
Narasimhan, S.,Balakrishnan, M.,Kumar, A. S.,Venkatasubramanian, N.
, p. 568 - 570 (2007/10/02)
Reductive methylation of amine salts by aqueous formaldehyde under acidic conditions proceeds through the initial formation of hydroxymethylamine intermediates, followed by intramolecular hydride transfer. 13C NMR studies on this reaction and the mechanism are discussed.