2840-02-0

Basic information

• Product Name: 5-AMINO-2-BROMOBENZOIC ACID
• Synonyms: 5-AMINO-2-BROMOBENZOIC ACID;4-Bromo-3-carboxyaniline;2-Bromo-5-aminobenzoic acid;5-Amino-2-bromobenzoic acid 94%
• CAS NO: 2840-02-0
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Phenylacetic acid;Aromatic Amino AcidsCarbonyl Compounds;C7;Carboxylic Acids;Peptide Synthesis;Unnatural Amino Acid Derivatives
• Mol File: 2840-02-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 171-179 °C
• Boiling Point: 366.2 °C at 760 mmHg
• Flash Point: 175.2 °C
• Appearance: /
• Density: 1.794 g/cm³
• Vapor Pressure: 5.26E-06mmHg at 25°C
• Refractive Index: 1.672
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 5-AMINO-2-BROMOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-2-BROMOBENZOIC ACID(2840-02-0)
• EPA Substance Registry System: 5-AMINO-2-BROMOBENZOIC ACID(2840-02-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 2840-02-0(Hazardous Substances Data)

Usage

Description

5-AMINO-2-BROMOBENZOIC ACID is an organic compound characterized as a white crystalline solid. It is known for its potential applications in the pharmaceutical and chemical industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
5-AMINO-2-BROMOBENZOIC ACID is used as a key intermediate compound for the synthesis of various pharmaceutical products. Its chemical structure allows it to be a building block for developing new drugs with specific therapeutic applications.
Used in Chemical Synthesis:
5-AMINO-2-BROMOBENZOIC ACID serves as a versatile reagent in chemical synthesis, particularly for creating novel organic compounds with potential applications in various fields, such as materials science, agrochemicals, and dyes.
Used in FABP4 Inhibition:
5-AMINO-2-BROMOBENZOIC ACID is used as an inhibitor for FABP4 (Fatty Acid Binding Protein 4) and FABP5 (Fatty Acid Binding Protein 5) to prevent or treat FABP4/5 related diseases. By targeting these proteins, it may help in managing conditions associated with fatty acid metabolism and transport, such as obesity, diabetes, and cardiovascular diseases.

Purification Methods

Crystallise the acid from H2O or *C6H6 (m 128o). The acetyl derivative crystallises from H2O (as monohydrate) or absolute EtOH with m 196-197o (anhydrous). [Koopal Rec Trav Chim, Pays Bas 34 148 1915, Bamberger Chem Ber 57 2090 1924, Beilstein 14 H 413, 14 II 245.]

InChI:InChI=1/C7H6BrNO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,9H2,(H,10,11)

Upstream product

• 943-14-6 2-bromo-5-nitrobenzoic acid 
• 64-19-7 acetic acid 
• 99-05-8 meta-aminobenzoic acid 

Downstream Products

• 1035235-21-2 2-bromo-5-(dimethylamino)benzoic acid 
• 752969-45-2 (5-amino-2-bromophenyl)methanol 
• 810696-50-5 6-bromo-3-(1-methoxycarbonyl-1-methylethyl)amino-2-nitrobenzoic acid methyl ester 

Relevant articles and documents

3-HYDROXY-6H-BENZO [C] CHROMENE-6-ONE DERIVATIVE AND MANUFACTURING METHOD THEREOF

A method of manufacturing a compound or a salt thereof expressed with a formula (III) below, characterized by causing a compound or a salt thereof expressed with a formula (I) below and a compound or a salt thereof expressed with a formula (II) below to r