2845-85-4

Basic information

• Product Name: 4-chloroisophthalic acid
• Synonyms: 4-chloroisophthalic acid;4-Chloro-1,3-benzenedicarboxylic acid;4-Chlorobenzene-1,3-dicarboxylic acid;1,3-Benzenedicarboxylic acid, 4-chloro-;Isophthalic acid, 4-chloro-
• CAS NO: 2845-85-4
• Molecular Formula: C₈H₅ClO₄
• Molecular Weight: 200.58
• Mol File: 2845-85-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: >290 °C
• Boiling Point: 424.9°Cat760mmHg
• Flash Point: 210.8°C
• Appearance: /
• Density: 1.586g/cm³
• Vapor Pressure: 5.59E-08mmHg at 25°C
• Refractive Index: 1.63
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.51±0.25(Predicted)
• CAS DataBase Reference: 4-chloroisophthalic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloroisophthalic acid(2845-85-4)
• EPA Substance Registry System: 4-chloroisophthalic acid(2845-85-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 2845-85-4(Hazardous Substances Data)

Usage

General Description

4-chloroisophthalic acid is a compound with the chemical formula C8H5ClO4. It is a derivative of isophthalic acid, with a chlorine atom substituted for one of the hydrogen atoms on the benzene ring. 4-chloroisophthalic acid is widely used in the production of high-performance polymers, such as polyesters, due to its ability to modify the properties of the resulting materials. It is also used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Additionally, 4-chloroisophthalic acid has applications in the development of functional materials, including liquid crystals, and as a reagent in organic synthesis. Its versatility and utility in various industries make it an important chemical in the field of organic chemistry and materials science.

InChI:InChI=1/C8H5ClO4/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3H,(H,10,11)(H,12,13)

Upstream product

• 95-66-9 2,4-dimethylchlorobenzene 
• 73129-52-9 2'-chloro-5-methylacetophenone 
• 37074-39-8 4-chloro-3-methylacetophenone 
• 13520-08-6 1-chloro-2,4-bis-dichloromethyl-benzene 
• 7446-70-0 aluminium trichloride 
• 122-01-0 4-chloro-benzoyl chloride 
• 10025-87-3 trichlorophosphate 
• 118-91-2 ortho-chlorobenzoic acid 
• 96576-98-6 (E)-1,4-bis(4-chloro-3-methylphenyl)-2-butene-1,4-dione 
• 2845-84-3 4-chloroisophthalaldehyde 

Downstream Products

• 779349-89-2 4-methylamino-isophthalic acid 
• 13519-90-9 2,4-dicyano-1-fluorobenzene 
• 4387-30-8 4-chloro-1,3-benzenedicarbonitrile 
• 13520-07-5 4-morpholinoisophthalonitrile 
• 41779-14-0 5-Benzylamino-N-methyl-4-phenoxy-isophthalamic acid 
• 41779-26-4 Aethyl-4-anilino-5-carboxy-3-nitro-benzoat 
• 41884-03-1 5-Benzylamino-N-(2-methoxy-ethyl)-4-phenoxy-isophthalamic acid 
• 41779-45-7 5-Benzylamino-4-(4-chloro-phenylsulfanyl)-isophthalic acid diethyl ester 
• 41779-16-2 5-Benzylamino-N-butyl-4-phenoxy-isophthalamic acid 
• 41779-42-4 5-Benzylamino-4-phenylsulfanyl-isophthalic acid diethyl ester 
• 41779-48-0 5-Benzylamino-4-phenoxy-isophthalic acid diethyl ester 
• 41779-09-3 5-Benzylamino-N-(2-hydroxy-ethyl)-4-phenylsulfanyl-isophthalamic acid 
• 41779-10-6 5-Benzylamino-4-(4-chloro-phenylsulfanyl)-isophthalic acid 3-ethyl ester 
• 41779-38-8 5-Benzylamino-N,N-dimethyl-4-phenylamino-isophthalamic acid ethyl ester 

Relevant articles and documents

Electrophilicity and nucleophilicity of commonly used aldehydes

The present approach for determining the electrophilicity (E) and nucleophilicity (N) of aldehydes includes a kinetic study of KMNO4 oxidation and NaBH4 reduction of aldehydes. A transition state analysis of the KMNO4 promoted aldehyde oxidation reaction has been performed, which shows a very good correlation with experimental results. The validity of the experimental method has been tested using the experimental activation parameters of the two reactions. The utility of the present approach is further demonstrated by the theoretical versus experimental relationship, which provides easy access to E and N values for various aldehydes and offers an at-a-glance assessment of the chemical reactivity of aldehydes in various reactions. the Partner Organisations 2014.