28494-48-6 Usage
Description
4-NITRO-1H-PYRROLE-2-CARBOHYDRAZIDE is a chemical compound with the molecular formula C5H5N5O3. It is a yellow crystalline solid that is commonly used in organic synthesis and medicinal chemistry. As a derivative of pyrrole, it contains a nitro group and a carbohydrazide moiety, making it a versatile reagent in the synthesis of various organic compounds and a building block for pharmaceutical intermediates. Its potential biological activities and pharmacological properties have also been studied, highlighting its importance in the field of organic chemistry and drug development.
Uses
Used in Organic Synthesis:
4-NITRO-1H-PYRROLE-2-CARBOHYDRAZIDE is used as a reagent for the synthesis of various organic compounds due to its reactivity and the presence of the nitro and carbohydrazide functional groups.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-NITRO-1H-PYRROLE-2-CARBOHYDRAZIDE serves as a building block for the preparation of pharmaceutical intermediates, contributing to the development of new drugs and therapeutic agents.
Used in Drug Development:
4-NITRO-1H-PYRROLE-2-CARBOHYDRAZIDE is utilized in drug development for its potential biological activities and pharmacological properties, which are being studied to explore its therapeutic applications and effects on various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 28494-48-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,4,9 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 28494-48:
(7*2)+(6*8)+(5*4)+(4*9)+(3*4)+(2*4)+(1*8)=146
146 % 10 = 6
So 28494-48-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N4O3/c6-8-5(10)4-1-3(2-7-4)9(11)12/h1-2,7H,6H2,(H,8,10)
28494-48-6Relevant articles and documents
Synthesis of novel 4-nitropyrrole-based semicarbazide and thiosemicarbazide hybrids with antimicrobial and anti-tubercular activity
Rane, Rajesh A.,Naphade, Shital S.,Bangalore, Pavan Kumar,Palkar, Mahesh B.,Shaikh, Mahamadhanif S.,Karpoormath, Rajshekhar
, p. 3079 - 3083 (2014/06/24)
We report the synthesis and screening of forty novel 4-nitropyrrole- semicarbazide conjugates inspired from the reported bio-potential of bromopyrrole alkaloids and semicarbazide derivatives for antimicrobial activity. Herein, hybrids 5k-5o, 5r, 5s and 5t
Synthesis and evaluation of novel 4-nitropyrrole-based 1,3,4-oxadiazole derivatives as antimicrobial and anti-tubercular agents
Rane, Rajesh A.,Bangalore, Pavankumar,Borhade, Sheetal D.,Khandare, Preeti K.
, p. 49 - 58 (2013/11/06)
We report synthesis and antimicrobial evaluation of 42 novel 4-nitropyrrole-based 1,3,4-oxadiazoles. The synthesized molecules were evaluated for anti-bacterial, anti-fungal and anti-tubercular activities. Promisingly, most of the compounds showed equal o