28540-82-1 Usage
Description
Tentoxin, a highly effective phytotoxin from Alternaria alternata f. sp. tenuis, is a natural cyclic tetrapeptide that induces chlorosis in plants. It is selectively phytotoxic and inhibits chloroplast development, resulting in chlorotic tissue. However, it is too expensive to be used as a commercial herbicide, and efforts to discover a cheaper, synthetic analogue with similar herbicidal properties have failed.
Uses
Used in Agriculture:
Tentoxin is used as a potential natural herbicide for [application reason] as it selectively targets and kills a number of important weeds at concentrations that have no effects on several important crops.
Used in Research and Development:
Tentoxin is used as a research tool for [application reason] to study its herbicidal properties and to explore the possibility of developing a cheaper, synthetic analogue with similar effects.
Check Digit Verification of cas no
The CAS Registry Mumber 28540-82-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,5,4 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28540-82:
(7*2)+(6*8)+(5*5)+(4*4)+(3*0)+(2*8)+(1*2)=121
121 % 10 = 1
So 28540-82-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H30N4O4/c1-14(2)11-17-22(30)26(5)18(12-16-9-7-6-8-10-16)21(29)23-13-19(27)25(4)15(3)20(28)24-17/h6-10,12,14-15,17H,11,13H2,1-5H3,(H,23,29)(H,24,28)/b18-12-/t15-,17-/m0/s1
28540-82-1Relevant articles and documents
Tentoxin as a scaffold for drug discovery. Total solid-phase synthesis of tentoxin and a library of analogues
Jimenez, Jose C.,Chavarria, Bibiana,Lopez-Macia, Angel,Royo, Miriam,Giralt, Ernest,Albericio, Fernando
, p. 2115 - 2118 (2007/10/03)
(Matrix presented) A solid-phase method for the synthesis of tentoxin has been developed. Two key steps - dehydration and N-alkylation - are carried out while the peptide is anchored to the resin. The method, which has been validated by the preparation of