2856-63-5 Usage
Description
2-Chlorobenzyl cyanide, also known as 2-(4-chlorophenyl)acetonitrile, is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is characterized by its clear, slightly yellow liquid appearance after melting and possesses valuable chemical properties that make it a versatile building block in the chemical industry.
Uses
Used in Pharmaceutical Industry:
2-Chlorobenzyl cyanide is used as a key intermediate in the synthesis of clopidogrel, a potent platelet aggregation inhibitor. It plays a crucial role in the development of this medication, which is widely prescribed for the prevention of blood clots and the treatment of conditions such as atherosclerosis, recent heart attack, and stroke.
Additionally, due to its unique chemical structure, 2-Chlorobenzyl cyanide can be further utilized in the synthesis of other pharmaceutical compounds, contributing to the development of new drugs and therapies in the healthcare sector.
Used in Agrochemical Industry:
2-Chlorobenzyl cyanide also finds application in the agrochemical industry, where it is used as a starting material for the synthesis of various pesticides and insecticides. Its chemical properties make it a valuable component in the development of these products, which are essential for protecting crops and ensuring food security.
Check Digit Verification of cas no
The CAS Registry Mumber 2856-63-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,5 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2856-63:
(6*2)+(5*8)+(4*5)+(3*6)+(2*6)+(1*3)=105
105 % 10 = 5
So 2856-63-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClN/c9-8-4-2-1-3-7(8)5-6-10/h1-4H,5H2
2856-63-5Relevant articles and documents
Rapid and Simple Access to α-(Hetero)arylacetonitriles from Gem-Difluoroalkenes
Hu, Dandan,Liu, Jiayue,Ren, Hongjun,Song, Jinyu,Zhang, Jun-Qi,Zhu, Guorong
supporting information, p. 786 - 790 (2022/01/28)
A scalable cyanation of gem-difluoroalkenes to (hetero)arylacetonitrile derivatives was developed. This strategy features mild reaction conditions, excellent yields, wide substrate scope, and broad functional group tolerance. Significantly, in this reacti
Ionic liquid-induced conversion of methoxymethyl-protected alcohols into nitriles and iodides using [Hmim][NO3]
Noei, Jalil,Mirjafari, Arsalan
supporting information, p. 4424 - 4426 (2014/08/05)
This Letter reports a one-pot efficient conversion of methoxymethyl-ethers into their corresponding nitriles and iodides using the ionic liquid, 1-methyl-3H-imidazolium nitrate ([Hmim][NO3]) under microwave irradiation. A variety of products were prepared in high yields using this method.
Pd-catalyzed cyanation of benzyl chlorides with nontoxic K 4[Fe(CN)6]
Ren, Yunlai,Yan, Mengjie,Zhao, Shuang,Sun, Yanpei,Wang, Jianji,Yin, Weiping,Liu, Zhifei
scheme or table, p. 5107 - 5109 (2011/10/05)
Non-toxic K4[Fe(CN)6] was demonstrated to be effective as a green cyanating agent for the cyanation of alkyl halides using PPh3/Pd(OAc)2 as a catalyst system. The presented method allowed a series of benzyl chlorides to be smoothly cyanated in up to 88% yield. In order to avoid or suppress the deactivation of the catalyst, the reaction was required to be performed in a stringent inert ambiance.