285988-23-0

Basic information

• Product Name: (3S,5E,2'S)-N-{2-[5-(2'-(methoxymethyl)pyrrolidin-1'-ylimino)-2,2-dimethyl-[1,3]dioxan-4-yl]ethyl}-4-methylbenzenesulfonamide
• Synonyms: (3S,5E,2'S)-N-{2-[5-(2'-(methoxymethyl)pyrrolidin-1'-ylimino)-2,2-dimethyl-[1,3]dioxan-4-yl]ethyl}-4-methylbenzenesulfonamide
• CAS NO: 285988-23-0
• Molecular Weight: 439.576
• Mol File: 285988-23-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S,5E,2'S)-N-{2-[5-(2'-(methoxymethyl)pyrrolidin-1'-ylimino)-2,2-dimethyl-[1,3]dioxan-4-yl]ethyl}-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5E,2'S)-N-{2-[5-(2'-(methoxymethyl)pyrrolidin-1'-ylimino)-2,2-dimethyl-[1,3]dioxan-4-yl]ethyl}-4-methylbenzenesulfonamide(285988-23-0)
• EPA Substance Registry System: (3S,5E,2'S)-N-{2-[5-(2'-(methoxymethyl)pyrrolidin-1'-ylimino)-2,2-dimethyl-[1,3]dioxan-4-yl]ethyl}-4-methylbenzenesulfonamide(285988-23-0)

Safety Data

• Hazardous Substances Data: 285988-23-0(Hazardous Substances Data)

Upstream product

• 3634-89-7 N-(p-toluenesulfonyl)aziridine 
• 126178-07-2 (S)-(+)-1-(2,2-dimethyl-1,3-dioxan-5-ylidenamino)-2-methoxymethylpyrrolidine 

Relevant articles and documents

Asymmetric synthesis of γ-amino ketones and nitriles via β-aminoethylation of SAMP-hydrazones with tosylaziridine

The asymmetric synthesis of γ-amino nitriles 4a-c and γ-amino ketones 5d-f is described. Key step of the procedure is the diastereoselective β-aminoethylation of metalated SAMP-/RAMP-hydrazones 1a-f with tosylaziridine 2. Cleavage of the chiral auxiliary with MMPP leads to γ-amino nitriles 4a-c in good yields and excellent enantiomeric excesses (ee ≥ 98%). Likewise γ-amino ketones 5d-f (ee ≥ 98%) were obtained in good overall yields by cleavage of the hydrazones 3d-f with aqueous copper(II) chloride solution. Thieme Stuttgart.