28639-18-1

Basic information

• Product Name: 1-(Hydroxymethyl)hexahydro-1H-pyrrolizine
• Synonyms: 1-(Hydroxymethyl)hexahydro-1H-pyrrolizine;Hexahydro-1H-pyrrolizine-1-methanol
• CAS NO: 28639-18-1
• Molecular Formula: C₈H₁₅NO
• Molecular Weight: 0
• Mol File: 28639-18-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(Hydroxymethyl)hexahydro-1H-pyrrolizine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Hydroxymethyl)hexahydro-1H-pyrrolizine(28639-18-1)
• EPA Substance Registry System: 1-(Hydroxymethyl)hexahydro-1H-pyrrolizine(28639-18-1)

Safety Data

• Hazardous Substances Data: 28639-18-1(Hazardous Substances Data)

Usage

Molar mass

141.21 g/mol

Classification

Heterocyclic compound

Ring structure

Contains nitrogen

Pharmaceutical research

Used in drug development

Potential applications

Medication for neurological disorders and conditions

Unique structure

Interest in neurotransmitter and brain function studies

Intermediate compound

Used in synthesis of other organic molecules with therapeutic applications

Role in pharmaceuticals

Significant in development and research

Field of medicine

Potential for further research and development

Upstream product

• 90978-65-7 hexahydro-pyrrolizine-1-carboxylic acid ethyl ester 
• 103142-97-8 1-(4-Azido-butyryl)-cyclopropanecarboxylic acid methyl ester 
• 103143-02-8 6-Azido-3-oxo-hexanoic acid methyl ester 
• 87281-38-7 2,5,6,7-Tetrahydro-3H-pyrrolizine-1-carboxylic acid methyl ester 
• 174363-59-8 1-(5-Hydroxypent-3-enyl)-2-(trimethylsilyl)pyrrolidine 
• 174363-56-5 1-(5-Hydroxypent-3-ynyl)-2-(trimethylsilyl)pyrrolidine 
• 145388-46-1 1-(5-Chloropent-3-enyl)-2-(trimethylsilyl)pyrrolidine 
• 174680-23-0 2-Trimethylsilanyl-1-trimethylsilanylmethyl-pyrrolidine 
• 87556-56-7 Hexahydro-pyrrolizine-1-carbaldehyde 
• 7529-17-1 N-methylpyrrolidine N-oxide 
• 107-18-6 allyl alcohol 
• 54514-96-4 methylisoretronecanolate 
• 103143-04-0 1-(4,5-Dihydro-3H-pyrrol-2-yl)-cyclopropanecarboxylic acid methyl ester 

Downstream Products

• 100971-28-6 C₆H₃N₃O₇*C₈H₁₅NO 

Relevant articles and documents

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ARYL-SUBSTITUTED POLYCYCLIC AMINES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT

The invention relates to aryl-substituted polycyclic amines of formula I, particularly bicyclic amines, and the physiologically acceptable salts and physiologically functional derivatives thereof, the symbols and radicals being defined as indicated in the description.

Sequential two-electron oxidation of α,α′-disilylmethylamines to generate non-stabilized azomethine ylide: An ideal approach for the construction of substituted and fused pyrrolidine ring systems

α,α′-Di(trimethylsilylmethyl)amines undergo sequential double desilylation processes, by two-electron oxidation initiated either by photoinduced electron transfer (PET) or Ag(I)F, to produce non-stabilized azomethine ylides efficiently which upon trapping with appropriate dipolarophiles give the corresponding pyrrolidines. Application of this strategy to cyclic analogue for the rapid construction of biologically important 1-azabicyclo[m,3.0]alkane framework is discussed.