286844-91-5 Usage
General Description
1-(4-(Trifluoromethoxy)phenoxy)-4-(methylsulfonyl)benzene, also known as sulfonyl fluoride, is a chemical compound with the molecular formula C14H11F3O4S. It is a white solid that is insoluble in water but soluble in organic solvents. 1-(4-(TRIFLUOROMETHOXY)PHENOXY)-4-(METHYLSULFONYL)BENZENE is commonly used as a building block in organic synthesis and pharmaceutical research, and it is also employed as a reagent in the synthesis of various pharmaceuticals and agrochemicals. Sulfonyl fluoride has been found to exhibit potential anti-inflammatory properties and has been investigated for its potential use in the treatment of inflammatory diseases. Additionally, this compound is used as a probe to label and identify nucleophiles in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 286844-91-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,6,8,4 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 286844-91:
(8*2)+(7*8)+(6*6)+(5*8)+(4*4)+(3*4)+(2*9)+(1*1)=195
195 % 10 = 5
So 286844-91-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H11F3O4S/c1-22(18,19)13-8-6-11(7-9-13)20-10-2-4-12(5-3-10)21-14(15,16)17/h2-9H,1H3
286844-91-5Relevant articles and documents
The development of a large-scale synthesis of matrix metalloproteinase inhibitor, ABT-518
Chang, Sou-Jen,Fernando, Dilinie,Fickes, Michael,Gupta, Ashok K.,Hill, David R.,McDermott, Todd,Parekh, Shyamal,Tian, Zhenping,Wittenberger, Steven J.
, p. 329 - 335 (2002)
A process for the preparation of matrix metalloproteinase inhibitor ABT-518 has been developed. Significant improvements have been made to the first generation synthesis and are described here. The new process is very robust and efficient; multikilogram quantities of the title compound have been synthesized for clinical trials. ABT-518 was prepared by this six-step synthetic sequence in 51% overall yield with >99% ee.
Process for the selective N-formylation of N-hydroxylamines
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Example 4, (2010/01/30)
The instant invention provides a process for the selective N-formylation of N-hydroxylamines.
Process for the selective N-formylation of N-hydroxylamines
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, (2008/06/13)
The instant invention provides a process for the selective N-formylation of N-hydroxylamines.
