287114-25-4

Basic information

• Product Name: tert-Butyl 8-aza-bicyclo[3.2.1]octan-3-ylcarbamate
• Synonyms: tert-Butyl 8-aza-bicyclo[3.2.1]octan-3-ylcarbamate;TERT-BUTYL 8-AZABICYCLO[3.2.1]OCT-3-YLCARBAMATE;3-(Boc-aMino)-8-azabicyclo[3.2.1]octane;tert-Butyl 8-azabicyclo[3.2.1]octan-3-ylcarbamate, >=97%
• CAS NO: 287114-25-4
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 226.31
• Mol File: 287114-25-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 339.8 °C at 760 mmHg
• Flash Point: 159.3 °C
• Appearance: /
• Density: 1.07 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• PKA: 12.36±0.20(Predicted)
• CAS DataBase Reference: tert-Butyl 8-aza-bicyclo[3.2.1]octan-3-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 8-aza-bicyclo[3.2.1]octan-3-ylcarbamate(287114-25-4)
• EPA Substance Registry System: tert-Butyl 8-aza-bicyclo[3.2.1]octan-3-ylcarbamate(287114-25-4)

Safety Data

• Hazardous Substances Data: 287114-25-4(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 8-aza-bicyclo[3.2.1]octan-3-ylcarbamate is a chemical compound with a complex structure containing the carbamate functional group. It is used as a reagent in organic synthesis, particularly for the synthesis of complex molecules and pharmaceuticals. tert-Butyl 8-aza-bicyclo[3.2.1]octan-3-ylcarbamate is known for its stability and ability to facilitate selective reactions in organic chemistry. Its tert-butyl and 8-aza-bicyclo[3.2.1]octan-3-yl substituents contribute to its unique properties, making it a valuable component in the development of new chemical compounds and materials.

Upstream product

• 287114-24-3 (8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-carbamic acid tert-butyl ester 

Downstream Products

• 1363400-82-1 tert-butyl 8-(2-methoxy-6-pentadecylbenzyl)-8-azabicyclo[3,2,1]octan-3-ylcarbamate 
• 1392889-06-3 C₂₄H₃₀N₈S 
• 1239893-94-7 N-{(1S)-2-(3-amino-8-azabicyclo[3.2.1]oct-8-yl)-1-[(4-bromophenyl)methyl]-2-oxoethyl}-1-(2,4-dichlorophenyl)cyclopropanecarboxamide 
• 1239893-92-5 N-{(1S)-2-(3-amino-8-azabicyclo[3.2.1]oct-8-yl)-1-[(2,4-dichlorophenyl)methyl]-2-oxoethyl}-1-(2,4-dichlorophenyl)cyclopropanecarboxamide 

Relevant articles and documents

BENZOFUROPYRIMIDINONES AS PROTEIN KINASE INHIBITORS

A compound according to formula I: or a pharmaceutically acceptable salt thereof; wherein R1, R2, R3a, R3b, R3c and R3d are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.

MEDICINAL COMPOSITION

The present invention is composed of a pharmaceutical composition for the therapy of nephritis which comprises an amide derivative represented by the following formula [1] or pharmaceutically acceptable salt thereof, as an active ingredient: ???wherein R1 and R2 may be the same or different and each is hydrogen, alkyl which may be substituted, acyl, aryl which may be substituted, or an aromatic heterocyclic group which may be substituted; R3, R4, R5 and R6 may be the same or different and each is hydrogen, halogen, hydroxy, amino which may be substituted, alkyl which may be substituted, alkoxy or nitro and the like; and R7 represents cyclic amino which may be substituted or azabicycloalkylamino which may be substituted. The pharmaceutical composition of the invention is useful for the therapy of nephritis.