2878-60-6

Basic information

• Product Name: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropanamide
• Synonyms: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropanamide
• CAS NO: 2878-60-6
• Molecular Formula: C₁₉H₂₃NO₃
• Molecular Weight: 313.39082
• Mol File: 2878-60-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropanamide(2878-60-6)
• EPA Substance Registry System: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylpropanamide(2878-60-6)

Safety Data

• Hazardous Substances Data: 2878-60-6(Hazardous Substances Data)

Upstream product

• 501-52-0 3-Phenylpropionic acid 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 621-82-9 Cinnamic acid 
• 56361-03-6 N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenylacrylamide 
• 645-45-4 hydrocinnamic acid chloride 

Downstream Products

• 1430088-67-7 styelsamine-N¹⁴-3-phenylpropanamide 
• 1430088-71-3 cystodytin-N¹⁴-3-phenylpropanamide 
• 1430088-76-8 O-methyl styelsamine-N¹⁴-2-phenylacetamide 
• 1430088-78-0 O-methyl styelsamine-N¹⁴-3-phenylpropanamide 
• 81305-67-1 3,4-dihydro-6,7-dimethoxy-1-(2-phenylethyl)isoquinoline 
• 29903-68-2 (+/-)-6,7-dimethoxy-1-[2-(phenyl)ethyl]-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

Enhancement of the carbamate activation rate enabled syntheses of tetracyclic benzolactams: 8-oxoberbines and their 5- And 7-membered C-ring homologues

A route to the direct amidation of aromatic-ring-tetheredN-carbamoyl tetrahydroisoquinoline substrates was developed. This route enabled general access to 8-oxoberberines and their 5- and 7- membered C-ring homologues. It overcomes the undesired tandem side-reactions that result in the destruction of the isoquinoline backbone, which inevitably occurred under our previously reported superacidic carbamate activation method.

Synthesis and structure activity relationship of tetrahydroisoquinoline- based potentiators of GluN2C and GluN2D containing N-Methyl-D-aspartate receptors

We describe here the synthesis and evaluation of a series of tetrahydroisoquinolines that show subunit-selective potentiation of NMDA receptors containing the GluN2C or GluN2D subunits. Bischler-Napieralski conditions were employed in the key step for the