287964-59-4

Basic information

• Product Name: Cyanotemozolomide
• Synonyms: Cyanotemozolomide;3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbonitrile;Cyano TeMozoMide;IMidazo[5,1-c][1,2,4]triazine-8-carboxaMide,1,4-dihydro-3-nitro-4-oxo-;Cyanotemozolomide, >=98%;Temozolomide Impurity G
• CAS NO: 287964-59-4
• Molecular Formula: C6H4N6O4
• Molecular Weight: 224.13376
• Product Categories: Pharmaceutical intermediate
• Mol File: 287964-59-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 415.285 °C at 760 mmHg
• Flash Point: 204.958 °C
• Appearance: /
• Density: 1.743 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.84
• PKA: 14.41±0.20(Predicted)
• CAS DataBase Reference: Cyanotemozolomide(CAS DataBase Reference)
• NIST Chemistry Reference: Cyanotemozolomide(287964-59-4)
• EPA Substance Registry System: Cyanotemozolomide(287964-59-4)

Safety Data

• Hazardous Substances Data: 287964-59-4(Hazardous Substances Data)

Usage

Uses

Cyanotemozolomide is a derivative of temozolomide (T01775), which is an antineoplastic agent.

InChI:InChI=1/C6H4N6O/c1-11-6(13)12-3-8-4(2-7)5(12)9-10-11/h3H,1H3

Upstream product

• 287964-47-0 2-(5-carbamoyl-3H-imidazol-4-ylazo)-2-nitro-malonic acid diethyl ester 
• 287964-78-7 4-chloro-3-nitro-imidazo[5,1-c][1,2,4]triazine-8-carboxylic acid amide 

Relevant articles and documents

Synthesis of 1,4-dihydroimidazo[5,1-c]-1,2,4-triazin-4-ones and imidazo[5,1-c]-1,2,4-triazoles

Azo compounds obtained by the coupling of 5-diazoimidazoles with diethyl esters of nitro-, chloro-, bromo-, and acetylaminomalonic acids under conditions of base catalysis are cyclized to give 1,4-dihydroimidazo[5,1-c]-1,2,4-triazin-4-ones or imidazo[5,1-