288251-69-4

Basic information

• Product Name: 1-(4-fluorophenyl)-3-formylpyrrole
• Synonyms: 1-(4-fluorophenyl)-3-formylpyrrole
• CAS NO: 288251-69-4
• Molecular Weight: 189.189
• Mol File: 288251-69-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(4-fluorophenyl)-3-formylpyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-fluorophenyl)-3-formylpyrrole(288251-69-4)
• EPA Substance Registry System: 1-(4-fluorophenyl)-3-formylpyrrole(288251-69-4)

Safety Data

• Hazardous Substances Data: 288251-69-4(Hazardous Substances Data)

Upstream product

• 81329-31-9 1-(4-fluorophenyl)-1H-pyrrole 
• 371-40-4 4-fluoroaniline 
• 169036-71-9 1-(4-fluorophenyl)-2-formylpyrrole 
• 50634-05-4 2,5-dimethoxy-3-tetrahydrofurancarboxaldehyde 

Downstream Products

• 288250-76-0 N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288249-80-9 N-[3-cyano-4-piperidinophenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288249-65-0 N-[3-cyano-4-(2,2,2-trifluoroethyl)phenyl]-1-(4-fluorophenyl)pyrrole-3-carboxamide 
• 288251-68-3 1-(4-fluorophenyl)pyrrole-3-carboxylic acid 
• 691863-10-2 methanesulfonic acid 3-[1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-2-oxo-oxazolidin-5-ylmethyl ester 
• 691863-22-6 5-azidomethyl-3-[1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 
• 691862-86-9 [1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-carbamic acid benzyl ester 
• 691863-34-0 5-aminomethyl-3-[1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 
• 691862-98-3 3-[1-(4-fluoro-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one 

Relevant articles and documents

AMIDOPYRIDINE DERIVATIVE, AND USE THEREOF

The present invention relates to novel amidopyridine derivatives. More specifically, the present invention provides a medicinal agent which is useful as a prophylactic or therapeutic agent for diseases based on the production of cytokines from T cells, comprising as the active ingredient an amidopyridine derivative or a pharmacologically acceptable salt thereof. Provided are an amidopyridine derivative of the following general formula (I): wherein each symbol has the same meaning as defined in the description, or a pharmacologically acceptable salt thereof.

Novel HIV-1 protease inhibitors active against multiple PI-Resistant viral strains: Coadministration with indinavir

HIV-1 protease inhibitors (PI) with an N-arylpyrrole moiety in the P 3 position afforded excellent antiviral potency and substantially improved aqueous solubility over previously reported variants. The rapid in vitro clearance of these compounds in human liver microsomes prompted oral coadministration with indinavir to hinder their metabolism by the cyctochrome P450 3A4 isozyme and allow for in vivo PK assessment.