288252-12-0

Basic information

• Product Name: Benzonitrile, 5-amino-2-[1,4'-bipiperidin]-1'-yl-
• CAS NO: 288252-12-0
• Molecular Formula: C17H24N4
• Molecular Weight: 284.404
• Mol File: 288252-12-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 5-amino-2-[1,4'-bipiperidin]-1'-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 5-amino-2-[1,4'-bipiperidin]-1'-yl-(288252-12-0)
• EPA Substance Registry System: Benzonitrile, 5-amino-2-[1,4'-bipiperidin]-1'-yl-(288252-12-0)

Safety Data

• Hazardous Substances Data: 288252-12-0(Hazardous Substances Data)

Upstream product

• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 16588-02-6 4-chloro-3-cyanonitrobenzene 
• 16588-15-1 2-chloro-5-nitro-benzamide 
• 6130-94-5 1-(piperidin-1-yl)piperidine 

Downstream Products

• 288250-87-3 1-(4-chlorophenyl)-N-[3-cyano-4-(4-piperidinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide 
• 398137-07-0 N-[3-cyano-4-(4-piperidinopiperidin-1-yl)phenyl]benzo[b]thiophene-2-carboxamide 

Relevant articles and documents

Fused bicyclic amide compounds and medicinal use thereof

The present invention provides a compound represented by the formula (I) wherein ring A is benzene, cyclohexane, pyridine, piperidine or a derivative thereof, imidazole or a derivative thereof and the like, ring B is benzene, cyclohexane, pyrrole or a derivative thereof, furan, thiophene and the like, R1, R2 and R3 are each hydrogen, alkyl, halogen, hydroxyl group, alkoxy and the like, W is hydrogen, alkyl or hydroxycarbonylalkyl, X is halogen, cyano, nitro and the like, X′ is hydrogen, halogen and the like, and Y is alkyl, hydroxyalkyl, hydroxycarbonylalkyl, aminoalkyl and the like, a salt thereof, and a pharmaceutical agent containing the compound. The compound of the present invention shows a superior inhibitory effect on the proliferation of activated lymphocyte and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.