2885-00-9 Usage
Description
1-Octadecanethiol (ODT) is a water-soluble sulfur compound with an 18-carbon alkyl chain, known for its strong hydrophobic assembly with transition metals, such as gold. It forms self-assembled monolayers (SAMs) on the surface of these transition metals, exhibiting an electrostriction phenomenon when covalently bonded with the metal electrode, leading to variations in capacitance. ODT SAMs have a hydrophobic surface with a contact angle of 102oC. It is a white powder with an extremely unpleasant smell.
Uses
Used in Organic Synthesis:
Octadecanethiol is used as an organic intermediate for various chemical reactions and processes, contributing to the synthesis of different compounds.
Used in Synthetic Rubber Processing:
Octadecanethiol is utilized in the processing of synthetic rubber, enhancing its properties and performance in various applications.
Used in Surface Modification:
Octadecanethiol is used for surface modification of gold nanoparticles (AuNPs) and Nickel (Ni) foam conjugate, preparing a 3D surface-enhanced Raman spectroscopy (SERS) substrate for the detection of organic pollutants. It may also be used to enhance the superhydrophobic properties of different materials, such as nano-sized copper films, graphene, and silica, for applications like mercury detection and electrochemical analysis.
Used in Molecular Deposition:
1-Octadecanethiol (ODT) is employed to deposit thiolated molecules onto the surface of gold substrates, such as SAMs on gold quartz crystal resonators and on the tip of atomic force microscope probes, as well as capacitive sensors.
Reactivity Profile
Octadecanethiol is non-flammable but combustible (Flash point >100°F and <140°F). Incompatible with oxidizing agents, strong acids and strong bases, alkali metals, and nitric acid. Can react with water, steam or acids to produce toxic and flammable vapors. Reacts violently with powerful oxidizing agents such as calcium hypochlorite(Ca(OCl)2) to generate SOx. Reacts with hydrides to form flammable H2 gas; reacts with halogenated hydrocarbons to yield HX. Reacts exothermically with aldehydes. Emits toxic compounds of sulfur when when heated to decomposition.
Hazard
Strong irritant.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 2885-00-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,8 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2885-00:
(6*2)+(5*8)+(4*8)+(3*5)+(2*0)+(1*0)=99
99 % 10 = 9
So 2885-00-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H38S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h19H,2-18H2,1H3
2885-00-9Relevant articles and documents
Amphiphilic dendrimer, synthesis method thereof, and application of amphiphilic dendrimer as drug delivery system
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Paragraph 0096-0097; 0108-0110; 0123-0124; 0132-0134, (2021/08/07)
The invention relates to a microenvironment response type amphiphilic dendrimer, a synthesis method thereof, and application of the microenvironment response type amphiphilic dendrimer as a drug delivery system. The microenvironment response type amphiphilic dendrimer is a compound with a structure as shown in a formula (I), a formula (II) or a formula (III) or pharmaceutically acceptable salt of the compound. The compound disclosed by the invention can be used as the nano delivery system based on tumor microenvironment specific response, has good solubility in an aqueous solution, can be self-assembled with a drug in the aqueous solution to form a relatively stable nano compound, can effectively deliver the loaded drug to a tumor site; and can responsively disassembl the nano-drug delivery carrier under corresponding stimulation to achieve the purpose of accurate drug release, so that the drug can be released to the focus part to the greatest extent, and the compound is a novel nano-delivery carrier.
Synthetic method for the preparation of 1,2-Benzisothiazolin-3-one
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Paragraph 0158, (2015/12/18)
The present invention relates to a method for producing a 1,2-benzisothiazolin-3-one compound (I) by reacting a 2-halobenzonitrile compound (II) with a thiol compound (III) to form an intermediate (IV) and subsequently reacting the intermediate (IV) with a halogenation agent in the presence of water to form a reaction mixture (RM), comprising the 1,2-benzisothiazolin-3-one compound (I) and a halide compound (V). R3-SH (III), R3_X1(V),
L-Cysteine as a water-soluble cation scavenger in the removal of the 2,4,6-trimethoxybenzyl group from thiols
Lin, Chia-En,Richardson, Stewart K,Garvey, David S
, p. 4531 - 4533 (2007/10/03)
L-Cysteine was used as a water-soluble cation scavenger in the acid-catalyzed removal of the 2,4,6-trimethoxybenzyl (Tmob) group from thiols. After aqueous extraction, the product thiols were isolated in good yields. For most substrates, trifluoroacetic acid (TFA) is the reagent of choice. However, for the deprotection of acid-sensitive compounds, formic acid with an extended reaction time is appropriate.
