288623-94-9

Basic information

• Product Name: N-(2-{2-[2-(3-dimethylamino-propylcarbamoyl)-1-methyl-1H-imidazol-4-ylcarbamoyl]-1-methyl-1H-imidazol-4-ylcarbamoyl}-1-methyl-1H-imidazol-4-yl)-terephthalamic acid
• CAS NO: 288623-94-9
• Molecular Weight: 619.64
• Mol File: 288623-94-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-{2-[2-(3-dimethylamino-propylcarbamoyl)-1-methyl-1H-imidazol-4-ylcarbamoyl]-1-methyl-1H-imidazol-4-ylcarbamoyl}-1-methyl-1H-imidazol-4-yl)-terephthalamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-{2-[2-(3-dimethylamino-propylcarbamoyl)-1-methyl-1H-imidazol-4-ylcarbamoyl]-1-methyl-1H-imidazol-4-ylcarbamoyl}-1-methyl-1H-imidazol-4-yl)-terephthalamic acid(288623-94-9)
• EPA Substance Registry System: N-(2-{2-[2-(3-dimethylamino-propylcarbamoyl)-1-methyl-1H-imidazol-4-ylcarbamoyl]-1-methyl-1H-imidazol-4-ylcarbamoyl}-1-methyl-1H-imidazol-4-yl)-terephthalamic acid(288623-94-9)

Safety Data

• Hazardous Substances Data: 288623-94-9(Hazardous Substances Data)

Upstream product

• 288623-83-6 N-[3-(dimethylamino)propyl]-1-methyl-4-[(1-methyl-4-nitroimidazole-2-carboxamido)imidazole-2-carboxamido]imidazole-2-carboxamide 
• 329038-98-4 NCH₃CCONCNCHNH(CH₂)3N(CH₃)2H₂COCN₂CH₂CHCNH₂COCN₂CH₂CNH₂CH 
• 463326-45-6 NCH₃CCONCNCHNH(CH₂)3N(CH₃)2H₂COCN₂CH₂CHCNO₂ 
• 463326-47-8 NCH₃CCONCNCHNH(CH₂)3N(CH₃)2H₂COCN₂CH₂CHCNH₂ 
• 160751-31-5 4-Amino-1-methyl-1H-imidazole-2-carboxylic acid (3-dimethylamino-propyl)-amide 
• 109-55-7 1-amino-3-(dimethylamino)propane 
• 128484-08-2 N-[3-(dimethylamino)propyl]-1-methyl-4-nitroimidazole-2-carboxamide 
• 120095-64-9 2,2,2-trichloro-1-(1-methyl-4-nitro-1H-imidazol-2-yl)ethan-1-one 
• 288623-86-9 N-(2-{2-[2-(3-dimethylamino-propylcarbamoyl)-1-methyl-1H-imidazol-4-ylcarbamoyl]-1-methyl-1H-imidazol-4-ylcarbamoyl}-1-methyl-1H-imidazol-4-yl)-terephthalamic acid methyl ester 

Relevant articles and documents

Synthesis of geometrically constrained unsymmetrical bis(polyamides) related to the antiviral distamycin

Analysis of the structural and stereochemical requirements for the strict DNA base-sequence recognition of (AT)4 and (AT)5, respectively, for the oligopeptide minor-groove binding agents netropsin (I) and distamycin (II) leads to proposals for the rational structure modification for altered base recognition. In this paper we report the synthesis of unsymmetrical imidazo-pyrrolo-bis(polyamides), structurally related to the natural antiviral agents distamycin, and bearing either unnatural (25-27) or natural (31-33) termini linked by a flexible or rigid linker. This is the first report of the synthesis of an imidazole-bearing structure with either dimethylaminopropyl or amidinium termini in the linked bis(polyamides).