289030-37-1

Basic information

• Product Name: 2-dichloromethyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester
• CAS NO: 289030-37-1
• Molecular Weight: 212.032
• Mol File: 289030-37-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 232.8±40.0 °C(Predicted)
• Density: 1.59±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-dichloromethyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-dichloromethyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester(289030-37-1)
• EPA Substance Registry System: 2-dichloromethyl-4,5-dihydrooxazole-4-carboxylic acid methyl ester(289030-37-1)

Safety Data

• Hazardous Substances Data: 289030-37-1(Hazardous Substances Data)

Upstream product

• 5619-04-5 methyl 2-amino-3-hydroxypropanoate hydrochloride 
• 3018-12-0 dichloroacetonitrile 
• 5680-80-8 methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride 
• 2104-89-4 Ser-OMe 
• 163769-70-8 1-methoxy-2,2-dichloroethylenimine 

Downstream Products

• 208465-72-9 methyl 2-(chloromethyl)-1,3-oxazole-4-carboxylate 
• 208465-69-4 (R)-((3R,4R,E)-7-((S,2E,4E)-8-(tert-butyldimethylsilyloxy)-6-(tert-butyldiphenylsilyloxy)-4-methylocta-2,4-dienylamino)-2,4-dimethyl-7-oxohept-5-en-3-yl) 1-(2-(chloromethyl)-oxazole-4-carbonyl)pyrrolidine-2-carboxylate 
• 208465-70-7 (R)-((3R,4R,E)-7-((S,2E,4E)-6-(tert-butyldiphenylsilyloxy)-8-hydroxy-4-methylocta-2,4-dienylamino)-2,4-dimethyl-7-oxohept-5-en-3-yl) 1-(2-(chloromethyl)oxazole-4-carbonyl)pyrrolidine-2-carboxylate 
• 208465-60-5 (R)-((3R,4R,E)-7-((S,2E,4E)-6-(tert-butyldiphenylsilyloxy)-4-methyl-8-oxoocta-2,4-dienylamino)-2,4-dimethyl-7-oxohept-5-en-3-yl) 1-(2-(iodomethyl)oxazole-4-carbonyl)pyrrolidine-2-carboxylate 
• 318279-50-4 C₄₄H₅₇N₃O₇Si 
• 1346661-79-7 C₄₄H₅₇N₃O₇Si 
• 1246937-61-0 (R)-((3R,4R,E)-7-((S,2E,4E)-6-(tert-butyldiphenylsilyloxy)-4-methyl-8-oxoocta-2,4-dienylamino)-2,4-dimethyl-7-oxohept-5-en-3-yl) 1-(2-(chloromethyl)oxazole-4-carbonyl)pyrrolidine-2-carboxylate 
• 1246937-60-9 (R)-benzyl 1-(2-(chloromethyl)oxazole-4-carbonyl)-pyrrolidine-2-carboxylate 
• 208465-67-2 2-iodomethyloxazole-4-carboxylic acid methyl ester 
• 866324-13-2 2-[(4R,6R,7E)-4,6-bis(tert-butyldimethylsilyloxy)-2-oxo-8-phenyl-7-octenyl]oxazole-4-carboxylic acid methyl ester 

Relevant articles and documents

MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS

Provided are compounds represented by Formula IA: (IA), and the pharmaceutically acceptable salts and solvates thereof, wherein R, R 1a, R 1b, L 1, L 2, L 3, X, A, B and C are as defined as set forth

N-[2-(3-AMINO-2,5-DIMETHYL-1,1-DIOXIDO-5,6-DIHYDRO-2H-1,2,4-THIADIAZIN-5-YL)-1,3-THIAZOL-4-YL] AMIDES USEFUL AS BACE INHIBITORS

The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, wherein the variables R1, R2 and R3/su

2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL-1,3-THIAZOL-4-YL AMIDES

The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula (I), and the variable R1 is as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.