2899-94-7 Usage
Type of compound
synthetic corticosteroid derivative
Main properties
anti-inflammatory and immunosuppressive
Availability
not commercially available as medication
Use
important intermediate in production of other corticosteroid drugs
Commonly used as a starting material in synthesis of other steroids
Can be converted into prednisolone, widely used oral corticosteroid
Chemical structure
similar to prednisone, with double bond at 20th position
Pharmacological properties altered due to double bond
Studies suggest higher anti-inflammatory effect compared to prednisone
Valuable compound in development of new corticosteroid medications.
Check Digit Verification of cas no
The CAS Registry Mumber 2899-94-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,9 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2899-94:
(6*2)+(5*8)+(4*9)+(3*9)+(2*9)+(1*4)=137
137 % 10 = 7
So 2899-94-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,17-18,22,25-26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,17?,18+,19-,20-,21-/m0/s1
2899-94-7Relevant articles and documents
Steroid transformations with Fusarium oxysporum var. cubense and Colletotrichum musae
Wilson, Maureen R.,Gallimore, Winklet A.,Reese, Paul B.
, p. 834 - 843 (2007/10/03)
The utility of two locally isolated fungi, pathogenic to banana, for steroid biotransformation has been studied. The deuteromycetes Fusarium oxysporum var. cubense (IMI 326069, UAMH 9013) and Colletotrichum musae (IMI 374528, UAMH 8929) had not been examined previously for this potential. In general, F. oxysporum var. cubense effected 7α hydroxylation on 3β-hydroxy- Δ5-steroids, 6β, 12β, and 15α hydroxylation on steroidal-4-ene-3-ones, side-chain degradation on 17α,21-dihydroxypregnene-3,20-diones, and 15α hydroxylation on estrone. Both strains were shown to perform redox reactions on alcohols and ketones.
