2900-11-0

Basic information

• Product Name: ethyl 1-(iodomethyl)-2-oxocyclohexanecarboxylate
• Synonyms: ethyl 1-(iodomethyl)-2-oxocyclohexanecarboxylate
• CAS NO: 2900-11-0
• Molecular Weight: 310.132
• Mol File: 2900-11-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 1-(iodomethyl)-2-oxocyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(iodomethyl)-2-oxocyclohexanecarboxylate(2900-11-0)
• EPA Substance Registry System: ethyl 1-(iodomethyl)-2-oxocyclohexanecarboxylate(2900-11-0)

Safety Data

• Hazardous Substances Data: 2900-11-0(Hazardous Substances Data)

Upstream product

• 75-11-6 diiodomethane 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 

Downstream Products

• 1276046-20-8 7-benzyl 1-ethyl 2-methyleneheptanedioate 
• 33229-02-6 2-methyleneheptanedioic acid 
• 1276046-25-3 ethyl 7-(benzylamino)-2-methylene-7-oxoheptanoate 
• 1246655-02-6 C₃₉H₅₄O₁₂ 
• 1246655-10-6 C₁₂₆H₁₇₄O₃₆S₃ 
• 66088-37-7 ethyl 1-methyl-2-oxocyclohexancarboxylate 

Relevant articles and documents

The Grob/Eschenmoser fragmentation of cycloalkanones bearing β-electron withdrawing groups: A general strategy to acyclic synthetic intermediates

Introduction of a β-electron withdrawing group to cycloalkanones allows facile C-C bond fragmentation. The reaction has been demonstrated with a large range of ring sizes, bearing various leaving and electron withdrawing groups, and using a variety of nitrogen and oxygen containing nucleophiles (>30 examples). The application of fragmentation products to the preparation of substituted γ-lactones has been demonstrated. Mechanistic studies are reported which are suggestive of a Grob/Eschenmoser type reaction.