29006-06-2Relevant articles and documents
A novel tin-free procedure for alkyl radical reactions
Benati, Luisa,Leardini, Rino,Minozzi, Matteo,Nanni, Daniele,Scialpi, Rosanna,Spagnolo, Piero,Strazzari, Samantha,Zanardi, Giuseppe
, p. 3598 - 3601 (2007/10/03)
Desulfuration as a source of alkyl radicals: The addition of alkylsulfanyl radicals to isocyanides gives the corresponding alkyl radicals. This methodology can replace the usual tin-mediated radical procedures and allows for the generation of tertiary, secondary, and even nonstabilized primary radicals that can be used efficiently in reductive defunctionalizations and intermolecular additions to electron-rich olefins (see scheme).
