2906-39-0 Usage
Description
3,4-dihydro-2H-pyrrole-2-carboxylic acid is an organic compound belonging to the pyrrole family, characterized by a five-membered nitrogen-containing ring structure. It is a derivative of 1-pyrrolinecarboxylic acid, where one of the hydrogens at position 2 is replaced by a carboxy group. 3,4-dihydro-2H-pyrrole-2-carboxylic acid plays a significant role in various biological processes and has potential applications in different industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3,4-dihydro-2H-pyrrole-2-carboxylic acid is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs targeting specific biological pathways.
Used in Metabolic Research:
In the field of metabolic research, 3,4-dihydro-2H-pyrrole-2-carboxylic acid serves as an important intermediate in the metabolic interconversion of glutamic acid and proline. This makes it a valuable compound for studying the metabolic pathways and understanding the role of these amino acids in cellular processes.
Used in Antimicrobial Applications:
3,4-dihydro-2H-pyrrole-2-carboxylic acid is used as an antimicrobial agent, particularly against Trypanosoma cruzi, the parasite responsible for Chagas disease. It supports mitochondrial metabolism and host-cell invasion, which can help in the development of new treatments for this disease.
Used in Chemical Synthesis:
Due to its unique chemical structure, 3,4-dihydro-2H-pyrrole-2-carboxylic acid is used as a building block in the synthesis of various organic compounds. It can be employed in the production of specialty chemicals, dyes, and other materials with specific properties.
Used in Material Science:
3,4-dihydro-2H-pyrrole-2-carboxylic acid's structural properties make it a potential candidate for use in the development of new materials with specific characteristics, such as conductivity, magnetism, or optical properties. It can be utilized in the research and development of advanced materials for various applications, including electronics, sensors, and energy storage devices.
Check Digit Verification of cas no
The CAS Registry Mumber 2906-39-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,0 and 6 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2906-39:
(6*2)+(5*9)+(4*0)+(3*6)+(2*3)+(1*9)=90
90 % 10 = 0
So 2906-39-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H7NO2/c7-5(8)4-2-1-3-6-4/h3-4H,1-2H2,(H,7,8)
2906-39-0Relevant articles and documents
Synthesis and evaluation of effective inhibitors of plant δ1-pyrroline-5-carboxylate reductase
Forlani, Giuseppe,Berlicki, Lukasz,Duo, Mattia,Dziedziola, Gabriela,Giberti, Samuele,Bertazzini, Michele,Kafarski, Pawel
, p. 6792 - 6798 (2013/08/23)
Analogues of previously studied phenyl-substituted aminomethylene- bisphosphonic acids were synthesized and evaluated as inhibitors of Arabidopsis thaliana δ1-pyrroline-5-carboxylate reductase. With the aim of improving their effectiveness, two main modifications were introduced into the inhibitory scaffold: the aminomethylenebisphosphonic moiety was replaced with a hydroxymethylenebisphosphonic group, and the length of the molecule was increased by replacing the methylene linker with an ethylidene chain. In addition, chlorine atoms in the phenyl ring were replaced with various other substituents. Most of the studied derivatives showed activity in the micromolar to millimolar range, with two of them being more effective than the lead compound, with concentrations inhibiting 50% of enzyme activity as low as 50 μM. Experimental evidence supporting the ability of these inhibitors to interfere with proline synthesis in vivo is also shown.
