29147-88-4

Basic information

• Product Name: 4-N-HEPTYLOXYBENZONITRILE
• Synonyms: P-(HEPTYLOXY)BENZONITRILE;4-N-HEPTYLOXYBENZONITRILE;4-HEPTYLOXYBENZONITRILE
• CAS NO: 29147-88-4
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.31
• Product Categories: Aromatic Nitriles;Nitrile;Anisoles, Alkyloxy Compounds & Phenylacetates;Nitriles
• Mol File: 29147-88-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 341.3 °C at 760 mmHg
• Flash Point: 144.1 °C
• Appearance: /
• Density: 0.98 g/cm³
• Vapor Pressure: 8.1E-05mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: 4-N-HEPTYLOXYBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-HEPTYLOXYBENZONITRILE(29147-88-4)
• EPA Substance Registry System: 4-N-HEPTYLOXYBENZONITRILE(29147-88-4)

Safety Data

• Hazardous Substances Data: 29147-88-4(Hazardous Substances Data)

Usage

General Description

4-N-Heptyloxybenzonitrile is a chemical compound with the molecular formula C16H23NO and a molecular weight of 245.36 g/mol. It is a nitrile derivative, featuring a nitrile group attached to a heptyloxybenzene core. 4-N-HEPTYLOXYBENZONITRILE is commonly used in research and industry, particularly in the synthesis of other organic compounds. It may also be used as a reagent in chemical reactions and as a building block for the creation of more complex molecules. Additionally, 4-N-heptyloxybenzonitrile may have potential applications in the development of pharmaceuticals and other bioactive compounds due to its versatile chemical structure.

InChI:InChI=1/C14H19NO/c1-2-3-4-5-6-11-16-14-9-7-13(12-15)8-10-14/h7-10H,2-6,11H2,1H3

Upstream product

• 629-04-9 1-Bromoheptane 
• 767-00-0 4-cyanophenol 
• 111-70-6 n-heptan1ol 
• 557-21-1 zinc(II) cyanide 
• 123732-04-7 4-n-heptyloxybromobenzene 

Downstream Products

• 77477-92-0 4-(heptyloxy)benzothioamide 
• 1443791-99-8 4-(4-bromophenyl)-2-(4-(heptyloxy)phenyl)thiazole 
• 1443792-00-4 (S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(2-(4-(heptyloxy)phenyl)thiazol-4-yl)phenyl)propanoate 
• 1443791-83-0 (S)-methyl 2-(4-(tert-butyl)benzamido)-3-(4-(3-(4-(heptyloxy)phenyl)-1,2,4-oxadiazol-5-yl)phenyl)propanoate 
• 1443791-84-1 (S)-methyl 2-(4-(tert-butyl)benzamido)-3-(4-(((4-(heptyloxy)benzimidamido)oxy)carbonyl)phenyl)propanoate 
• 1443788-24-6 (S)-2-(4-(tert-butyl)benzamido)-3-(4-(3-(4-(heptyloxy)phenyl)-1,2,4-oxadiazol-5-yl)phenyl)propanoic acid 
• 1443791-80-7 (Z)-4-(heptyloxy)-N’-hydroxybenzimidamide 
• 147080-46-4 4-Heptyloxy-N-hydroxy-benzamidine 

Relevant articles and documents

Pyrrolopyrrole aza boron dipyrromethene based two-photon fluorescent probes for subcellular imaging

A series of pyrrolopyrrole aza boron dipyrromethene derivatives have been designed and synthesised as two-photon fluorescent probes. The bisalkynyl analogues, having a donor-π-donor quadrupolar skeleton, show a red-shifted Q band at ca. 700 nm in toluene and a two-photon absorption (TPA) cross-section up to 2349 GM at 1040 nm. To enable these dyes to be used for subcellular imaging, a branched oligoethylene glycol unit has been introduced to enhance their hydrophilicity and biocompatibility, and a potential organelle-selective group, namely triphenylphosphonium or morpholine moiety has also been added with a view to targeting the mitochondria or lysosomes respectively. The resulting conjugates are essentially non-aggregated in deionised water, exhibiting an intense Q band at 668 nm and a TPA cross-section up to 384 GM at 1040 nm. These spectral features have been analysed using density functional theory calculations, which suggest that the TPA is mainly due to the S0 → S2 transition. In the subcellular imaging study, it has been found that the triphenylphosphonium-containing derivative can localise in the lysosomes of HeLa human cervical carcinoma cells, which may be a result of its positive charge and the negative logP value (-2.46, P = partition coefficient), while the morpholine-substituted analogue does not exhibit preferential subcellular localisation.

NOVEL GLP-1 RECEPTOR MODULATORS

Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36) and GLP-1(9-36), or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where "()" represents either or both the R and S form of the compound): where A, B, C, Y1, Y2, Z, R1, R2, R3, R4, R5, W1, n, p and q are as defined herein.

Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols nad alcohols

The synthesis of aryl ethers from phenols and alcohols using polymer- bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method