291518-56-4

Basic information

• Product Name: {1-[(4-methylphenyl)sulfonyl]-4-(nitrosothio)-4-piperidyl}methyl 7-[5-((1E)(3S)-3-hydroxyoct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]heptanoate
• Synonyms: {1-[(4-methylphenyl)sulfonyl]-4-(nitrosothio)-4-piperidyl}methyl 7-[5-((1E)(3S)-3-hydroxyoct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]heptanoate
• CAS NO: 291518-56-4
• Molecular Weight: 666.901
• Mol File: 291518-56-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {1-[(4-methylphenyl)sulfonyl]-4-(nitrosothio)-4-piperidyl}methyl 7-[5-((1E)(3S)-3-hydroxyoct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]heptanoate(CAS DataBase Reference)
• NIST Chemistry Reference: {1-[(4-methylphenyl)sulfonyl]-4-(nitrosothio)-4-piperidyl}methyl 7-[5-((1E)(3S)-3-hydroxyoct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]heptanoate(291518-56-4)
• EPA Substance Registry System: {1-[(4-methylphenyl)sulfonyl]-4-(nitrosothio)-4-piperidyl}methyl 7-[5-((1E)(3S)-3-hydroxyoct-1-enyl)(1R,4R,5R)-4-hydroxy-2-oxocyclopentyl]heptanoate(291518-56-4)

Safety Data

• Hazardous Substances Data: 291518-56-4(Hazardous Substances Data)

Upstream product

• 291518-68-8 4-(hydroxymethyl)-1-[(4-methylphenyl)sulfonyl]-4-(nitrosothio)piperidine 
• 745-65-3 ALPROSTADIL 

Relevant articles and documents

Nitrostated and nitrosylated prostaglandins, compositions and methods of use

The present invention describes novel nitrosated and/or nitrosylated prostaglandins, and novel compositions comprising at least one nitrosated and/or nitrosylated prostaglandin, and, optionally, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase, and/or at least one vasoactive agent. The present invention also provides novel compositions comprising at least one prostaglandin and at least one S-nitrosothiol compound, and, optionally, at least one vasoactive agent. The prostaglandin is preferably a prostaglandin E1 compound, more preferably alprostadil, and the S-nitrosothiol compound is preferably S-nitrosoglutathione. The present invention also provides methods for treating or preventing sexual dysfunctions in males and females, for enhancing sexual responses in males and females, and for treating or preventing cerebrovascular disorders, cardiovascular disorders, benign prostatic hyperplasia (BPH), glaucoma, peptic ulcers or for inducing abortions. The compounds and/or compositions of the present invention can also be provided in the form of a pharmaceutical kit.