29170-08-9

Basic information

• Product Name: 4-IODO-4'-NITROBIPHENYL
• Synonyms: iodonitrobiphenyl;4-iodo-4'-nitro-1,1'-biphenyl;4-IODO-4''-NITROBIPHENYL 98+%;4-Nitro-4'-iodo-1,1'-biphenyl;4-Nitro-4'-iodobiphenyl;1-(4-iodophenyl)-4-nitrobenzene;1-(4-iodophenyl)-4-nitro-benzene;1,1'-Biphenyl,4-iodo-4'-nitro-
• CAS NO: 29170-08-9
• Molecular Formula: C₁₂H₈INO₂
• Molecular Weight: 325.1
• EINECS: 249-480-5
• Product Categories: Biphenyl derivatives;biphenyl
• Mol File: 29170-08-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 216 °C
• Boiling Point: 397.7 °C at 760 mmHg
• Flash Point: 194.3 °C
• Appearance: /
• Density: 1.723 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility: Insoluble in water
• CAS DataBase Reference: 4-IODO-4'-NITROBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODO-4'-NITROBIPHENYL(29170-08-9)
• EPA Substance Registry System: 4-IODO-4'-NITROBIPHENYL(29170-08-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 29170-08-9(Hazardous Substances Data)

Usage

General Description

4-Iodo-4'-nitrobiphenyl is a chemical compound with the molecular formula C12H8IN02. It is a yellow solid at room temperature and is primarily used in the synthesis of other organic compounds. 4-IODO-4'-NITROBIPHENYL is known for its high melting and boiling points, as well as its insolubility in water. It is also considered to be a hazardous substance, as it is toxic if ingested or inhaled, and can cause skin and eye irritation upon contact. Additionally, 4-iodo-4'-nitrobiphenyl is a known irritant to the respiratory system and has the potential to cause long-term adverse effects on aquatic environments if released into the water.

Upstream product

• 92-52-4 biphenyl 
• 7553-56-2 iodine 
• 7697-37-2 nitric acid 
• 624-38-4 para-diiodobenzene 
• 171364-83-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene 
• 24067-17-2 4-nitrophenylboronic acid 
• 288608-09-3 1-(2,5-dimethyl-1H-pyrrol-1-yl)-4-iodobenzene 
• 3001-15-8 4,4'-diiodobiphenyl 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 7285-77-0 4-iodo-4'-aminobiphenyl 
• 25627-15-0 1,4'''-dinitro-4,1':4',1'':4'',1'''-quaterphenylene 
• 171889-71-7 4'-nitro-N-(m-tolyl)-N-(1-pyrenyl)-4-biphenylamine 
• 1191052-25-1 4-(4'-nitrobiphenyl)salicylalcohol isopropylidene acetal 
• 1374593-85-7 2-amino-5,5-dimethyl-4-[(4'-nitrobiphenyl-4-yl)methylidene]-2-oxazoline 
• 92-93-3 1-phenyl-4-nitrobenzene 
• 950193-44-9 FeC₅H₅C₅H₄C₂C₆H₄C₆H₄NO₂ 
• 284688-07-9 4'-ferrocenyl-4-nitro[1,1']biphenyl 
• 62579-50-4 1-(4'-iodo-4-nitro-biphenyl-3-yl)-piperidine 

Relevant articles and documents

Modular and Selective Arylation of Aryl Germanes (C?GeEt3) over C?Bpin, C?SiR3 and Halogens Enabled by Light-Activated Gold Catalysis

Selective C (Formula presented.) –C (Formula presented.) couplings are powerful strategies for the rapid and programmable construction of bi- or multiaryls. To this end, the next frontier of synthetic modularity will likely arise from harnessing the coupling space that is orthogonal to the powerful Pd-catalyzed coupling regime. This report details the realization of this concept and presents the fully selective arylation of aryl germanes (which are inert under Pd0/PdII catalysis) in the presence of the valuable functionalities C?BPin, C?SiMe3, C?I, C?Br, C?Cl, which in turn offer versatile opportunities for diversification. The protocol makes use of visible light activation combined with gold catalysis, which facilitates the selective coupling of C?Ge with aryl diazonium salts. Contrary to previous light-/gold-catalyzed couplings of Ar–N2+, which were specialized in Ar–N2+ scope, we present conditions to efficiently couple electron-rich, electron-poor, heterocyclic and sterically hindered aryl diazonium salts. Our computational data suggest that while electron-poor Ar–N2+ salts are readily activated by gold under blue-light irradiation, there is a competing dissociative deactivation pathway for excited electron-rich Ar–N2+, which requires an alternative photo-redox approach to enable productive couplings.

Efficient synthesis of N-alkyl-2,7-dihalocarbazoles by simultaneous carbazole ring closure and N-alkylation

The N-alkyl-2,7-dihalocarbazole as the main product was formed by the reaction of 4,4′-dihalo-2-nitrobiphenyl with aromatic nitro compound and trialkyl phosphite. The presence and crucial role of aromatic nitro compound causes simultaneous carbazole ring closure and N-alkylation unlike the Cadogan ring closure where non-alkylated carbazole is formed as a main product. In addition, the mixture of aromatic nitro compound and trialkyl phosphite was found to be a possible N-alkylating agent for heterocycles, such as carbazole or indole.

Synthesis of functionalized triazatriangulenes for application in photo- Switchable self-assembled monolayers

Various triazatriangulenes are synthesized by nucleophilic attack at the central C atom of triazatriangulenium ions. The molecular functions, especially azobenzenes, are fixed via an ethynyl linker by in situ deprotection of trimethylsilylalkynes. The structure of two of these molecules is further investigated by X-ray crystallography. The photo-inducedtrans/cis-isomerization of the azobenzene substituted derivatives is analyzed in solution and shows great promise for the preparation of switchable functionalized monolayers, as the triazatriangulenes are known for their self-assembly on gold surfaces. [1].