291753-13-4

Basic information

• Product Name: C₅₅H₆₅N₅O₁₃Si
• Synonyms: C₅₅H₆₅N₅O₁₃Si
• CAS NO: 291753-13-4
• Molecular Weight: 1032.23
• Mol File: 291753-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₅H₆₅N₅O₁₃Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₅H₆₅N₅O₁₃Si(291753-13-4)
• EPA Substance Registry System: C₅₅H₆₅N₅O₁₃Si(291753-13-4)

Safety Data

• Hazardous Substances Data: 291753-13-4(Hazardous Substances Data)

Upstream product

• 291753-09-8 4-benzyloxy-1-[5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidin-2-one 
• 291753-11-2 C₃₅H₄₉N₃O₇Si 
• 291753-10-1 4-benzyloxy-1-[4-(tert-butyl-dimethyl-silanyloxy)-5-hydroxymethyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidin-2-one 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 79722-21-7 tert-butyl N-(benzyloxy)carbamate 
• 291753-12-3 1-[5-(benzyloxyamino-methyl)-4-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 156939-39-8 Carbonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 4-nitro-phenyl ester 

Relevant articles and documents

Syntheses and binding studies of oligonucleotides containing N- hydroxycarbamate linkages: Potential DNA cleaving antisense oligomers

An efficient synthesis of N-hydroxycarbamate containing thymidine dimer 9 was accomplished and it was incorporated into automatic DNA syntheses to make thymidine 16mers T*-1, T*-2 and T*-3. Binding abilities of T*-1, T*-2 and T*-3 with poly (dA)-16mer were assayed by melting denaturation (Tm) studies of the corresponding duplexes. Iron binding ability of a thymidine oligomer with N-hydroxycarbamate linkages was studied by MALDI-MS. Nuclease stability assays showed that the modified oligonucleotides have enhanced resistance toward nuclease S1 (endonuclease) compared to natural oligonucleotides. (C) 2000 Elsevier Science Ltd.