291764-50-6

Basic information

• Product Name: 1-[2-(toluene-4-sylfoxy)-1-(acetoxymethyl)ethoxy]-methyl-2-nitroimidazole
• CAS NO: 291764-50-6
• Molecular Weight: 413.408
• Mol File: 291764-50-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-[2-(toluene-4-sylfoxy)-1-(acetoxymethyl)ethoxy]-methyl-2-nitroimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(toluene-4-sylfoxy)-1-(acetoxymethyl)ethoxy]-methyl-2-nitroimidazole(291764-50-6)
• EPA Substance Registry System: 1-[2-(toluene-4-sylfoxy)-1-(acetoxymethyl)ethoxy]-methyl-2-nitroimidazole(291764-50-6)

Safety Data

• Hazardous Substances Data: 291764-50-6(Hazardous Substances Data)

Upstream product

• 120398-89-2 RP-170 
• 98-59-9 p-toluenesulfonyl chloride 
• 291764-49-3 1-[2-hydroxy-1-(acetoxymethyl)ethoxy]-methyl-2-nitroimidazole 

Relevant articles and documents

METHOD FOR PRODUCING 2-NITROIMIDAZOLE DERIVATIVE

Disclosed is a method for producing a 2-nitroimidazole derivative having an acyclic sugar chain in a side chain which is suitable for production of a derivative having a radioisotope. Specifically disclosed is a method for producing 1-(1- benzoyloxymethyl

Synthesis of 1-[2-[18F]fluoro-1-(hydroxymethyl)-ethoxy]methyl-2-nitroimidazole ([18F]FENI), a potential agent for imaging hypoxie tissues by PET

Fluorine-18 labeled 1-[2-fluoro-1-(hydroxymethyl)ethoxy]-mehyl-2-nitroimidazole ([18F]FENI), a novel, potential radiotracer for imaging hypoxic tissue by PET, was synthesized. The [18F]FENI was prepared by nucleophilic 18F-fluorination of the precursor, 1-[2-(toluene-4-sulfoxy)-1-(acetoxymethyl)ethoxy]methyl-2-nitroimidazole, followed by deprotection and HPLC purification. Radiochemically pure [18F]FENI was obtained in overall yields of 3-11% (BOB) with specific activity of >26 GBq/nmol (EOS) within 90 min. Copyright