29212-22-4

Basic information

• Product Name: 5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID
• Synonyms: AKOS B029954;5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID;2-Thiophenecarboxylic acid, 5-Methoxy-;5-Methoxy-2-thiophenecarboxylic Acid
• CAS NO: 29212-22-4
• Molecular Formula: C₆H₆O₃S
• Molecular Weight: 158.18
• Mol File: 29212-22-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID(29212-22-4)
• EPA Substance Registry System: 5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID(29212-22-4)

Safety Data

• Hazardous Substances Data: 29212-22-4(Hazardous Substances Data)

Usage

Description

5-Methoxythiophene-2-carboxylic acid is a chemical compound with the molecular formula C7H6O3S. It is a carboxylic acid derivative of thiophene, containing a methoxy group at the 5-position of the thiophene ring. 5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID is known for its unique electronic and optical properties, making it a versatile building block in various industries.

Uses

Used in Pharmaceutical Industry:
5-Methoxythiophene-2-carboxylic acid is used as a key intermediate in the synthesis of various sulfonamide and azole drugs. Its presence in these drugs contributes to their therapeutic effects, particularly in treating bacterial and fungal infections.
Used in Agrochemical Industry:
5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID also serves as a building block in the development of agrochemicals, which are essential for enhancing crop protection and improving agricultural productivity.
Used in Material Science:
5-Methoxythiophene-2-carboxylic acid is utilized in material science due to its unique properties that can be harnessed to create advanced materials with specific characteristics.
Used in Organic Electronics:
5-METHOXYTHIOPHENE-2-CARBOXYLIC ACID's electronic and optical properties make it a valuable component in the field of organic electronics, where it can be used to develop novel electronic devices and systems with improved performance and functionality.

Upstream product

• 16839-97-7 2-methoxythiophene 
• 124-38-9 carbon dioxide 
• 109-72-8 n-butyllithium 
• 57070-77-6 5-bromo-2-methoxythiophene 

Downstream Products

• 42457-22-7 5-methoxythiophene-2-carbonyl chloride 

Relevant articles and documents

Catalyst-controlled regiodivergent C-H borylation of multifunctionalized heteroarenes by using iridium complexes

The regiodivergent C-H borylation of 2,5-disubstituted heteroarenes with bis(pinacolato)diboron was achieved by using iridium catalysts formed in situ from [Ir(OMe)(cod)]2/dtbpy (cod=1,5-cyclooctadiene, dtbpy: 4,4′-di-tert-butyl-2,2′-bipyridine) or [Ir(OMe)(cod)]2/2 AsPh3. When [Ir(OMe)(cod)]2/dtbpy was used as the catalyst, borylation at the 4-position proceeded selectively to afford 4-borylated products in high yields (dtbpy system A). The regioselectivity changed when the [Ir(OMe)(cod)]2/2 AsPh3 catalyst was used; 3-borylated products were obtained in high yields with high regioselectivity (AsPh3 system B). The regioselectivity of borylation was easily controlled by changing the ligands. This reaction was used in the syntheses of two different bioactive compound analogues by using the same starting material. Minor adjustments, major differences: The regiodivergent C-H borylation of 2,5-disubstituted heteroarenes with bis(pinacolato)diboron was achieved by using iridium catalysts formed in situ from [Ir(OMe)(cod)]2/dtbpy (cod=1,5-cyclooctadiene, dtbpy: 4,4'-di-tert-butyl-2,2'-bipyridine) or [Ir(OMe)(cod)]2/2 AsPh3 (see scheme).

Phosphorylamides, their preparation and use

A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.