29274-13-3

Basic information

• Product Name: 5-phenyl-4H-pyrazolo<1,5-a>pyrimidin-7-one
• Synonyms: 5-phenyl-4H-pyrazolo<1,5-a>pyrimidin-7-one
• CAS NO: 29274-13-3
• Molecular Weight: 211.223
• Mol File: 29274-13-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 5-phenyl-4H-pyrazolo<1,5-a>pyrimidin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenyl-4H-pyrazolo<1,5-a>pyrimidin-7-one(29274-13-3)
• EPA Substance Registry System: 5-phenyl-4H-pyrazolo<1,5-a>pyrimidin-7-one(29274-13-3)

Safety Data

• Hazardous Substances Data: 29274-13-3(Hazardous Substances Data)

Upstream product

• 37779-49-0 methyl 3-oxo-4-phenylbutanoate 
• 1225387-53-0 3⁽⁵⁾-aminopyrazole 
• 1820-80-0 3-aminopyrazole 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 672323-74-9 3-bromo-7-chloro-5-phenyl-pyrazolo[1,5-a]pyrimidine 
• 1112915-16-8 7-(1H-imidazol-4-yl)-5-phenyl-pyrazolo[1,5-a]pyrimidine 
• 1112915-13-5 7-(1-methyl-1H-indol-3-yl)-5-phenyl-pyrazolo[1,5-a]pyrimidine 
• 1112915-10-2 7-(1H-indol-3-yl)-5-phenyl-pyrazolo[1,5-a]pyrimidine 
• 1112915-07-7 7-(4-methoxy-naphthalen-1-yl)-5-phenyl-pyrazolo[1,5-a]pyrimidine 
• 1112915-04-4 4-(5-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-naphthalen-1-ol 
• 1112914-98-3 5-methoxy-2-(5-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-phenol 
• 1112914-96-1 4-(5-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-benzene-1,3-diol 
• 1112914-93-8 2-methyl-4-(5-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-benzene-1,3-diol 
• 1112914-91-6 5-phenyl-7-(2,4,6-trimethoxy-phenyl)-pyrazolo[1,5-a]pyrimidine 
• 77493-98-2 5-Phenyl-4H-pyrazolo[1,5-a]pyrimidine-7-thione 
• 244127-47-7 4'-<(5-phenylpyrazolo<1,5-a>pyrimidin-7-yl)aminomethyl>biphenyl-2-carbonitrile 
• 33149-25-6 7-chloro-5-phenyl-4H-pyrazolo[1,5-a]pyrimidine 

Relevant articles and documents

In silico design of novel probes for the atypical opioid receptor MRGPRX2

The primate-exclusive MRGPRX2 G protein-coupled receptor (GPCR) has been suggested to modulate pain and itch. Despite putative peptide and small-molecule MRGPRX2 agonists, selective nanomolar-potency probes have not yet been reported. To identify a MRGPRX

Evaluation of novel 7-(hetero)aryl-substituted pyrazolo[1, 5-a]pyrimidines as phosphodiesterase-4 inhibitors

A novel series of 7-(hetero)aryl substituted-pyrazolopyrimidines, prepared via an AlCl3 induced C-C bond forming reaction of 7-chloro-5-phenyl-pyrazolo[1,5-a]pyrimidine with arenes and heteroarenes have been investigated as PDE4 inhibitors. Amo

PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS

In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.