29287-66-9

Basic information

• Product Name: 1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• Synonyms: 1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-DIPALMITOYL-D62-3-SN-GLYCEROPHOSPHATIDYLCHOLINE;1,2-DIPALMITOYL-D62-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-O-DIHEXADECANOYL-D31-SN-GLYCERO-3-PHOSPHORYLCHOLINE;16:0 PC D62;37-1600-D62;DPPC (DIPALMITOYL-D62);L-ALPHA-PHOSPHATIDYLCHOLINE, DI(PALMITOYL-D31)
• CAS NO: 29287-66-9
• Molecular Formula: C40H18D62NO8P
• Molecular Weight: 796.42
• Mol File: 29287-66-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: 1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(29287-66-9)
• EPA Substance Registry System: 1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(29287-66-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 29287-66-9(Hazardous Substances Data)

Usage

Description

1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, also known as dilauroylphosphatidylcholine (DLPC), is a synthetic phospholipid that is widely used in lipid bilayer studies and as a component of liposomes. It features a glycerol backbone with two long hydrocarbon tails, one of which is saturated with deuterium atoms. This unique characteristic allows DLPC to be particularly useful for nuclear magnetic resonance (NMR) studies, as the deuterium atoms produce distinct signals in NMR spectra. DLPC serves as a model lipid for investigating lipid bilayer structure and dynamics, as well as for research in drug delivery and membrane biophysics. Its biocompatibility and stability make it a valuable tool in the study of membrane biology and drug formulation.

Uses

Used in Lipid Bilayer Studies:
1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is used as a model lipid for studying the structure and dynamics of lipid bilayers. Its unique deuterium-saturated hydrocarbon tail allows for detailed NMR analysis, providing insights into the behavior of lipid bilayers under various conditions.
Used in Drug Delivery Research:
1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is used as a component of liposomes in drug delivery research. Its biocompatibility and stability make it an ideal candidate for the development of drug delivery systems, enhancing the efficacy and targeting of therapeutic agents.
Used in Membrane Biophysics Research:
1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is used as a tool in membrane biophysics research to investigate the properties and interactions of biological membranes. Its distinct NMR signals contribute to a better understanding of membrane behavior and the role of lipids in cellular processes.
Used in Pharmaceutical Formulation:
1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is used in the development of pharmaceutical formulations, particularly for drugs that require encapsulation or targeted delivery. Its compatibility with biological systems and its role in liposome formation make it a valuable component in the creation of effective drug formulations.