294635-94-2Relevant articles and documents
Studies on arylfuran derivatives Part X. Synthesis and antibacterial properties of arylfuryl-Δ2-pyrazolines
Shivarama Holla,Akberali,Shivananda
, p. 256 - 263 (2007/10/03)
Arylfurylpropenones 3 were synthesized by Claisen-Schmidt condensation of arylfurfurals 1 with various substituted acetophenones 2. Cyclocondensation of these arylfurylpropenones 3 with hydrazine hydrate and phenylhydrazine furnished 1H-pyrazolines 4 and N-phenylpyrazolines 6, respectively. In order to study the structure-activity relationships, pyrazolines 4 were converted into their N-acetyl derivatives 5. The antibacterial properties of the new pyrazoline derivatives were studied. (C) 2000 Elsevier Science S.A.