294647-99-7

Basic information

• Product Name: 1H-Purin-6-amine, 2-chloro-N-[[4-(2-pyridinyl)phenyl]methyl]-
• CAS NO: 294647-99-7
• Molecular Formula: C17H13ClN6
• Molecular Weight: 336.783
• Mol File: 294647-99-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Purin-6-amine, 2-chloro-N-[[4-(2-pyridinyl)phenyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Purin-6-amine, 2-chloro-N-[[4-(2-pyridinyl)phenyl]methyl]-(294647-99-7)
• EPA Substance Registry System: 1H-Purin-6-amine, 2-chloro-N-[[4-(2-pyridinyl)phenyl]methyl]-(294647-99-7)

Safety Data

• Hazardous Substances Data: 294647-99-7(Hazardous Substances Data)

Upstream product

• 294647-97-5 1-[4-(pyridin-2-yl)phenyl]methanamine 
• 5451-40-1 2,6 dichloropurine 
• 5451-40-1 2,6-dichloro-7H-purine 

Downstream Products

• 294648-01-4 2-chloro-9-isopropyl-N-[[4-(2-pyridyl)phenyl]methyl]purin-6-amine 

Relevant articles and documents

REMOVAL OF SENESCENCE-ASSOCIATED MACROPHAGES

In various aspects and embodiments provided are compounds, compositions and methods relating to aging, senescent cells (SCs) and/or senescence associate macrophages (SAMs). In certain aspects and embodiments provided are compounds and compositions that selectively kill or reprogram senescent cells (SCs) and or senescence associate macrophages (SAMs) and associated methods. In some embodiments, the compounds compositions and methods treat or reverse aging and/or age-related diseases.

METHOD OF TREATMENT OF POLYCYSTIC DISEASES AND CHRONIC LYMPHOCYTIC LEUKEMIA

The present invention concerns a method of treatment of polycystic diseases or of reducing and/or avoiding cyst formation in a patient with cystic disease, which comprises at least one step consisting in administering to said patient an effective amount of a 2,6,9-trisubstituted purine compound of formula (VII): wherein A represents alternatively a (A.1) or (A.2) group.