29546-14-3

Basic information

• Product Name: 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N,N-dimethylaniline
• Synonyms: 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N,N-dimethylaniline
• CAS NO: 29546-14-3
• Molecular Weight: 252.319
• Mol File: 29546-14-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N,N-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N,N-dimethylaniline(29546-14-3)
• EPA Substance Registry System: 4-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N,N-dimethylaniline(29546-14-3)

Safety Data

• Hazardous Substances Data: 29546-14-3(Hazardous Substances Data)

Upstream product

• 54187-96-1 1-(chloromethyl)-1H-benzotriazole 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 95-14-7 1,2,3-Benzotriazole 
• 50-00-0 formaldehyd 
• 121-69-7 N,N-dimethyl-aniline 
• 88-74-4 2-nitro-aniline 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 28539-02-8 1-Hydroxymethyl-1H-benzotriazole 

Downstream Products

• 31859-50-4 3-((4-(N,N-Dimethylamino)phenyl)methyl)-indole 
• 46734-13-8 N,N-dimethyl-4-(phenylmethyl)benzenamine 
• 134627-84-2 1-((Benzotriazol-1-yl)-(4-(dimethylamino)phenyl)methyl)cyclohexan-1-ol 
• 129075-94-1 C₁₉H₂₆N₂ 
• 134627-76-2 C₂₂H₂₇N₃ 
• 134627-73-9 3-((4-(N,N-Dimethylamino)phenyl)methyl)-N-methylindole 
• 300679-48-5 2-(Benzotriazol-1-yl)-2-(4-(dimethylamino)phenyl)-1-(pyrid-4-yl)ethanol 
• 134627-95-5 1-(Pyrid-4-yl)-2-(4-(N,N-dimethylamino)phenyl)-2-(indol-3-yl)ethanol 
• 134627-94-4 1-(4-Tolyl)-2-(4-(N,N-dimethylamino)phenyl)-2-(indol-3-yl)ethanol 
• 134627-92-2 4-(Benzyl(indol-3-yl)methyl)-N,N-dimethylaniline 
• 134627-97-7 1-(4-(N,N-Dimethylamino)phenyl)-1-(4-(N,N-diethylamino)phenyl)ethane 
• 134627-91-1 3-(1-(4-(N,N-Dimethylamino)phenyl)ethyl)indole 
• 125379-44-4 3-(4-N,N-dimethylaminophenyl)pent-2-ene 
• 96558-51-9 p-(1-ethylpropyl)-NN-dimethylaniline 

Relevant articles and documents

One-Pot Synthesis of N-Alkyl Benzotriazoles via a Br?nsted Acid-Catalyzed Three-Component Reaction

A novel three-component condensation reaction of benzotriazoles, aldehydes and tertiary anilines efficiently catalyzed by readily available organic acid p-toluenesulfonic acid (PTSA) has been developed. A series of N-alkyl benzotriazoles were synthesized in up to 97% yield for 21 examples starting from anilines, benzotriazoles and formaldehyde. This strategy features a simple system, atom economy, environmental friendliness, high efficiency, excellent regioselectivity, good functional group tolerance, easily available starting materials, and cheap catalyst. The mechanistic studies indicated that aza quinone methide was probably involved as an intermediate in this transformation. (Figure presented.).

Synthesis of 1H-benzotriazoles via reductive amination on solid supports

An efficient synthesis of N-benzyl-1H-benzotriazoles utilizing a two-step reductive amination reaction on solid supports has been achieved. The method is suitable for combinatorial synthesis. Georg Thieme Verlag Stuttgart.

Benzotriazole-Mediated Stereoselective Olefination of Carboxylic Esters: Transformation of α-Amino Acid Esters into Chiral Allylamines

Diastereoselective trans-olefinations of carboxylic esters 3a-h have been accomplished using benzylic or allylic benzotriazole derivatives 1a-e to prepare α-(benzotriazol-1-yl) ketones 4a-i, for the subsequent reduction of 4a-i, and finally for low-valent titanium-effected dehydroxybenzotriazolylation.1 N-Protected α-amino acid esters 9a-c and 15 thus give allylamines 13a-e and 19 with virtually full retention of chirality. Mechanistic aspects of the dehydroxybenzotriazolylation are discussed.