296237-44-0Relevant articles and documents
New achievements in the field of intramolecular phenolic coupling reactions, using hypervalent (III) iodine reagent: Synthesis of galanthamine
Krikorian, Dikran,Tarpanov, Vclichko,Parushev, Stoyan,Mechkarova, Pepa
, p. 2833 - 2846 (2000)
Our investigations on the Oxidative possibilities of the hypervalent iodine(III) reagent established that phenyliodine(III)bis(trifluoroacctate (PIFA) can provide one-pot contiguous coupling-cyclization reaction giving a product with narwedine skeleton, when used in a phenolic coupling reaction of p'-bromonorbelladine derivatives. A suitably selected precursor gave up to 60% yield of the coupled product.