296274-75-4

Basic information

• Product Name: 5-((4-(tert-butyl)benzyl)thio)-1-phenyl-1H-tetrazole
• Synonyms: 5-((4-(tert-butyl)benzyl)thio)-1-phenyl-1H-tetrazole
• CAS NO: 296274-75-4
• Molecular Weight: 324.45
• Mol File: 296274-75-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-((4-(tert-butyl)benzyl)thio)-1-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-((4-(tert-butyl)benzyl)thio)-1-phenyl-1H-tetrazole(296274-75-4)
• EPA Substance Registry System: 5-((4-(tert-butyl)benzyl)thio)-1-phenyl-1H-tetrazole(296274-75-4)

Safety Data

• Hazardous Substances Data: 296274-75-4(Hazardous Substances Data)

Upstream product

• 5117-07-7 5,5'-dithiobis(1-phenyl-1H-tetrazole) 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 

Relevant articles and documents

Neutral sulfur nucleophiles: Synthesis of thioethers and thioesters by substitution reactions of N-heterocyclic carbene boryl sulfides and thioamides

Newly discovered boryl sulfides and N-borylthioamides are shown to serve as neutral sources of sulfur nucleophiles in substitutions reactions. For example, heating of diMe-Imd-BH(SPh)2 with benzyl bromides, primary bromides, or acid chlorides provides the corresponding thioethers or thioesters in high yields. Likewise, N-phenyltetrazole thioethers/esters are made from a readily available N-borylthionotetrazole. The formation of the boryl sulfide and its onward nucleophilic substitution can be telescoped down to a one-pot reaction whose components are an NHC-borane (NHC-BH3), a disulfide, and an electrophile.