Welcome to LookChem.com Sign In|Join Free

CAS

  • or

29682-14-2

Post Buying Request

29682-14-2 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

29682-14-2 Usage

Description

Methyl 5-nitro-2-pyridinecarboxylate is an organic compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its nitro group attached to the pyridine ring, which contributes to its reactivity and potential applications in the chemical and pharmaceutical industries.

Uses

Used in Pharmaceutical Industry:
Methyl 5-nitro-2-pyridinecarboxylate is used as an intermediate for the synthesis of 5-thio-2-pyridinecarboxylic acid derivatives, which possess antihypertensive activities. These derivatives are valuable in the development of medications aimed at treating high blood pressure and related cardiovascular conditions.
Methyl 5-nitro-2-pyridinecarboxylate plays a crucial role in the production of therapeutic agents that can help manage and reduce the risks associated with hypertension, making it an essential component in the pharmaceutical sector.

Check Digit Verification of cas no

The CAS Registry Mumber 29682-14-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,6,8 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 29682-14:
(7*2)+(6*9)+(5*6)+(4*8)+(3*2)+(2*1)+(1*4)=142
142 % 10 = 2
So 29682-14-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H6N2O4/c1-13-7(10)6-3-2-5(4-8-6)9(11)12/h2-4H,1H3

29682-14-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 5-nitropyridine-2-carboxylate

1.2 Other means of identification

Product number -
Other names 5-Nitro-2-methoxycarbonylpyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:29682-14-2 SDS

29682-14-2Relevant articles and documents

Molecular docking and enzymatic evaluation to identify selective inhibitors of aspartate semialdehyde dehydrogenase

Luniwal, Amarjit,Wang, Lin,Pavlovsky, Alexander,Erhardt, Paul W.,Viola, Ronald E.

, p. 2950 - 2956 (2012)

Microbes that have gained resistance against antibiotics pose a major emerging threat to human health. New targets must be identified that will guide the development of new classes of antibiotics. The selective inhibition of key microbial enzymes that are responsible for the biosynthesis of essential metabolites can be an effective way to counter this growing threat. Aspartate semialdehyde dehydrogenases (ASADHs) produce an early branch point metabolite in a microbial biosynthetic pathway for essential amino acids and for quorum sensing molecules. In this study, molecular modeling and docking studies were performed to achieve two key objectives that are important for the identification of new selective inhibitors of ASADH. First, virtual screening of a small library of compounds was used to identify new core structures that could serve as potential inhibitors of the ASADHs. Compounds have been identified from diverse chemical classes that are predicted to bind to ASADH with high affinity. Next, molecular docking studies were used to prioritize analogs within each class for synthesis and testing against representative bacterial forms of ASADH from Streptococcus pneumoniae and Vibrio cholerae. These studies have led to new micromolar inhibitors of ASADH, demonstrating the utility of this molecular modeling and docking approach for the identification of new classes of potential enzyme inhibitors.

N1-PYRAZOLOSPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS

-

, (2011/05/16)

The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt of the compound, wherein R1, R2, R3 and R4 are as described herein; pharmaceutical compositions there-of; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl- CoA carboxylase enzyme(s) in an animal

5-SUBSTITUTED ISOINDOLINE COMPOUNDS

-

Page/Page column 74, (2008/06/13)

-

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 29682-14-2