2980-33-8

Basic information

• Product Name: 2-HYDROXY-3,5-DINITROPYRIDINE
• Synonyms: 551945_ALDRICH;NSC 52198;NSC52198;Oprea1_319758;ST5409024;ZINC01683863;3,5-dinitro-2(1h)-pyridinon;3,5-DINITROPYRIDIN-2-OL
• CAS NO: 2980-33-8
• Molecular Formula: C₅H₃N₃O₅
• Molecular Weight: 185.09
• Product Categories: blocks;NitroCompounds;Pyridines;Pyridine;Heterocyclic Compounds;C5;Heterocyclic Building Blocks;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 2980-33-8.mol
• Article Data: 9

Chemical Properties

• Melting Point: 175-179 °C(lit.)
• Boiling Point: 319.28°C (rough estimate)
• Flash Point: 195.159 °C
• Appearance: /
• Density: 1.8469 (rough estimate)
• Vapor Pressure: 2.82E-06mmHg at 25°C
• Refractive Index: 1.5900 (estimate)
• PKA: 4.41±0.10(Predicted)
• BRN: 196025
• CAS DataBase Reference: 2-HYDROXY-3,5-DINITROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-3,5-DINITROPYRIDINE(2980-33-8)
• EPA Substance Registry System: 2-HYDROXY-3,5-DINITROPYRIDINE(2980-33-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: 2811
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 2980-33-8(Hazardous Substances Data)

Usage

Description

2-HYDROXY-3,5-DINITROPYRIDINE is an industrially significant nitropyridine derivative characterized by its yellow crystalline powder form. It is known for its potential applications in various chemical and industrial processes, particularly due to its unique chemical properties.

Uses

Used in Chemical Synthesis:
2-HYDROXY-3,5-DINITROPYRIDINE is used as a key intermediate in the synthesis of complex chemical compounds. Its unique structure allows for the creation of a variety of derivatives with diverse applications.
Used in Propellant Industry:
2-HYDROXY-3,5-DINITROPYRIDINE is used as a catalyst in the solid propellant industry. Its lead salt specifically finds application in this field, enhancing the performance and efficiency of solid propellants.
Used in Coordination Chemistry:
In coordination chemistry, 2-HYDROXY-3,5-DINITROPYRIDINE is used as a ligand to form metal complexes. An example of its application is in the preparation of bis([μ]-3,5-dinitro-pyridin-2-olato)bis-[tetra-aqua-(3,5-dinitro-pyridin-2-olato)barium(II)], which demonstrates its utility in creating complex and stable metal complexes.

InChI:InChI=1/C6H4N2O5/c9-5-4(8(12)13)1-3(2-7-5)6(10)11/h1-2H,(H,7,9)(H,10,11)

Upstream product

• 142-08-5 2-Pyridone 
• 5418-51-9 5-nitro-2-pyridone 
• 192825-36-8 2-(4-Bromo-phenylsulfanyl)-3,5-dinitro-pyridine 
• 31793-28-9 3,5-Dinitro-2-pyridyl-p-chlorphenylsulfid 
• 38082-90-5 3,5-dinitro-2-(phenylthio)pyridine 
• 142-08-5 2-hydroxypyridin 
• 1824-81-3 2-Amino-6-methylpyridine 
• 6635-31-0 6-hydroxy-5-nitronicotinic acid 
• 7697-37-2 nitric acid 
• 13472-80-5 2-hydroxy-3,5-diiodopyridine 
• 25864-34-0 2-amino-3,5-dinitro-6-methylpyridine 
• 2578-45-2 2-chloro-3,5-dinitropyridine 
• 6332-56-5 2-hydroxy-3-nitropyridine 
• 5418-51-9 5-nitro-2-hydroxypyridine 

Downstream Products

• 2578-45-2 2-chloro-3,5-dinitropyridine 
• 16420-30-7 2-bromo-3,5-dinitro-pyridine 
• 14150-94-8 3,5-dinitro-1-methyl-2-pyridone 
• 2075-46-9 4-nitro-1H-pyrazole 
• 497-18-7 carbonodihydrazide 
• 570409-62-0 t-butyl 8,8-dimethyl-3-nitro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate 
• 4318-78-9 3,5-diaminopyridine 
• 5667-38-9 3-amino-5-nitro-1H-pyridin-2-one 
• 945531-91-9 5-nitro-2-phenyloxazolo[5,4-b]pyridine 
• 52334-78-8 3-benzoylamino-5-nitro-1H-pyridin-2-one 
• 141421-13-8 2,5-diphenyloxazolo[ 5,4-b]pyridine 
• 5632-81-5 3,5-diamino-2-chloropyridine 

Relevant articles and documents

Solvent effect on the alkaline hydrolysis of 2-thiophenyl-3,5- dinitropyridine

The kinetics of the alkaline hydrolysis of 2-thiophenyl-3,5-dinitropyridine were studied spectrophotometrically in different aquo-organic solvents such as methanol, ethanol, n-propyl alcohol, iso-propyl alcohol, t-butyl alcohol, acetonitrile, dimethyl sulfoxide, dioxane, and acetone at 30°C with various solvent compositions up to 80% (v/v) of organic components, An increase in the organic solvent percentage (v/v) has different effects on the reaction rate constants presumably due to hydrogen bond donor HBD and acceptor HBA of the medium and other solvatochromic parameters. Linear and nonlinear plots of log k against the reciprocal of the dielectric constant of the solvent were obtained. The effects are too complex to be analyzed in terms of a single parameter, but an approach using the Kamlet-Taft solvatochromic parameters is applied successfullylo six mixed aquo-organic solvent systems.

Amino- and hydroxymethylation of hydride adducts of 2-hydroxy-3,5- dinitropyridine

A series of 1,5-dinitro-3,3-diazabicyclo[3.3.1]nonan-2-one derivatives has been synthesized by Mannich condensation of the hydride adduct of 2-hydroxy-3,5-dinitropyridine with formaldehyde and primary amines. The structure of the obtained compounds was proved by NMR spectroscopy.

Reactivity of heterocyclic compounds in nitration. 8. Nitration of 3-hydroxypyridine and its substituted forms

Nitration of 3-hydroxypyridine and its substituted forms has been studied under various conditions. It is shown that, depending on the reaction temperature and the nitrating agent, the end products of the synthesis can be 3-hydroxy-2,6-dinitropyridine or 3-hydroxy-2,4,6-trinitropyridine. The possibility of substitutional nitration of iodine derivatives of 2- and 3-hydroxypyridine is demonstrated. 1999 Kluwer Academic/Plenum Publishers.