298187-97-0 Usage
General Description
3-(1-[(4-Methylphenyl)sulfonyl]-1H-indol-3-yl)acrylic acid, also known as MSIA, is a chemical compound that contains a sulfonyl group, an indole ring, and an acrylic acid group. It is commonly used in pharmaceutical research and drug discovery due to its potential therapeutic properties. MSIA has been studied for its anti-inflammatory and anti-cancer activities, making it of interest for the development of novel drugs. Its structure and reactivity make it a valuable starting material for the synthesis of various bioactive molecules. Additionally, MSIA is also used as a building block in organic synthesis, allowing for the creation of complex organic molecules with unique functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 298187-97-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,8,1,8 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 298187-97:
(8*2)+(7*9)+(6*8)+(5*1)+(4*8)+(3*7)+(2*9)+(1*7)=210
210 % 10 = 0
So 298187-97-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H15NO4S/c1-13-6-9-15(10-7-13)24(22,23)19-12-14(8-11-18(20)21)16-4-2-3-5-17(16)19/h2-12H,1H3,(H,20,21)/b11-8+
298187-97-0Relevant articles and documents
Highly efficient and stereoselective N-vinylation of oxiranecarboxamides and unprecedented 8-endo-epoxy-arene cyclization: Expedient and biomimetic synthesis of some clausena alkaloids
Yang, Luo,Deng, Gang,Wang, De-Xian,Huang, Zhi-Tang,Zhu, Jie-Ping,Wang, Mei-Xiang
, p. 1387 - 1390 (2007/10/03)
Figure presented Catalyzed by Cul/N,N-dimethylglycine, oxiranecarboxamides underwent a highly efficient and stereoselective N-vinylation reaction with (Z)-1-aryl-2-bromoethenes to afford the corresponding enamides. The method has been applied to a straigh
Synthesis and serotonin receptor affinities of a series of trans-2- (indol-3-yl)cyclopropylamine derivatives
Vangveravong, Suwanna,Kanthasamy, Arthi,Lucaites, Virginia L.,Nelson, David L.,Nichols, David E.
, p. 4995 - 5001 (2007/10/03)
A series of four racemic ring-substituted trans-2-(indol-3- yl)cyclopropylamine derivatives was synthesized and tested for affinity at the 5-HT(1A) receptor, by competition with [3H]-8-OH-DPAT in rat hippocampal homogenates, and for affinity at