29866-18-0

Basic information

• Product Name: 6-benzyl-1H-purine
• Synonyms: 6-benzyl-1H-purine;1H-Purine, 6-(phenylmethyl)-;Nsc265417;6-BENZYL-9H-PURINE
• CAS NO: 29866-18-0
• Molecular Formula: C₁₂H₁₀N₄
• Molecular Weight: 210.2346
• EINECS: 249-900-7
• Mol File: 29866-18-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 366.5°Cat760mmHg
• Flash Point: 167.7°C
• Appearance: /
• Density: 1.32g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-benzyl-1H-purine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-benzyl-1H-purine(29866-18-0)
• EPA Substance Registry System: 6-benzyl-1H-purine(29866-18-0)

Safety Data

• Hazardous Substances Data: 29866-18-0(Hazardous Substances Data)

Usage

General Description

6-benzyl-1H-purine, also known as benzyladenine or BA, is a synthetic cytokinin that has a similar structure to adenine, a naturally occurring plant hormone. It has been widely used in plant tissue culture and horticulture to promote cell division and growth. 6-benzyl-1H-purine is often used to induce shoot development and improve the quality of plant regeneration from tissue culture. It has been found to have significant effects on the growth and development of various plant species, making it a valuable tool in plant biotechnology and agricultural practices. Additionally, 6-benzyl-1H-purine has also been studied for its potential applications in food preservation and as a therapeutic agent in medicine.

InChI:InChI=1/C12H10N4/c1-2-4-9(5-3-1)6-10-11-12(15-7-13-10)16-8-14-11/h1-5,7-8H,6H2,(H,13,14,15,16)

Upstream product

• 7306-68-5 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 
• 62673-31-8 benzyl(bromo)zinc 
• 862098-07-5 6-benzyl-9-(tetrahydro-pyran-2-yl)-9H-purine 
• 28493-54-1 benzyltributyltin 
• 87-42-3 6-chloropurine 

Relevant articles and documents

Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors

On the basis of ATP adenine, a series of adenine and purine derivatives was prepared and tested for their ability to inhibit a spectrum of disease-related kinases. There has been scant research investigating the potential of cosubstrate derived kinase inhibitors for other kinases than CDKs. Our inhibitor design combined the purine system from the original cosubstrate ATP and phenyl moieties in order to explore possible interactions with the different regions of the ATP binding site in several disease-related protein kinases. There have been a number of hits for the assayed substances, which led us to conclude that the spectrum of compounds may prove to be a valuable tool kit for the evaluation of bonding and selectivity patterns for a wide variety of kinases.

6-Chloropurines and organostannanes in palladium catalyzed cross coupling reactions

Carbon-carbon bond formation in the purine 6-position can easily be accomplished by palladium catalyzed cross coupling between 6-chloropurines and organostannanes without protection of the purine ring NH function. This technique provides a convenient route to cytokinines.