29956-84-1

Basic information

• Product Name: 3-chloro-2-hydroxybenzamide
• Synonyms: 3-chloro-2-hydroxybenzamide
• CAS NO: 29956-84-1
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.58104
• Mol File: 29956-84-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-chloro-2-hydroxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-2-hydroxybenzamide(29956-84-1)
• EPA Substance Registry System: 3-chloro-2-hydroxybenzamide(29956-84-1)

Safety Data

• Hazardous Substances Data: 29956-84-1(Hazardous Substances Data)

Upstream product

• 52159-67-8 methyl 3-chloro-2-hydroxybenzoate 
• 65-45-2 salicylamide 
• 1829-32-9 3-Chloro-2-hydroxybenzoic acid 
• 95-57-8 2-monochlorophenol 
• 116025-20-8 3-chloro-2-hydroxy-thiobenzoic acid S-methyl ester 
• 93820-08-7 3-chloro-2-hydroxybenzoyl chloride 

Downstream Products

• 873975-79-2 3-chloro-2-hydroxy-benzoic acid-(2,2,2-trichloro-1-hydroxy-ethylamide) 

Relevant articles and documents

Continuous-Flow Hofmann Rearrangement Using Trichloroisocyanuric Acid for the Preparation of 2-Benzoxazolinone

A continuous-flow preparation of 2-benzoxazolinone via the Hofmann rearrangement of salicylamide has been implemented employing trichloroisocyanuric acid as the stable and atom-economic chlorinating agent. The system was optimized to avoid solid accumulation and allow the preparation of hundreds of grams of the pure desired material over a working day. Furthermore, a trichloroisocyanuric acid (TCCA)-based chlorination of 2-benzoxazolone to the corresponding 5-chloro derivative was also carried out under batch conditions.

NOVEL SPIRO COMPOUNDS USEFUL AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desat- urase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.