3004-59-9

Basic information

• Product Name: Propanamide, N-2-benzothiazolyl- (9CI)
• Synonyms: Propanamide, N-2-benzothiazolyl- (9CI)
• CAS NO: 3004-59-9
• Molecular Formula: C10H10N2OS
• Molecular Weight: 206.2642
• Product Categories: BENZOTHIAZOLE
• Mol File: 3004-59-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Propanamide, N-2-benzothiazolyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-2-benzothiazolyl- (9CI)(3004-59-9)
• EPA Substance Registry System: Propanamide, N-2-benzothiazolyl- (9CI)(3004-59-9)

Safety Data

• Hazardous Substances Data: 3004-59-9(Hazardous Substances Data)

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 79-03-8 propionyl chloride 
• 1141-88-4 2-Aminophenyl disulfide 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Palladium-Catalyzed Direct Dicarbonylation of Amines with Ethylene to Imides

The selective and effective conversion of low-cost and simple bulk chemicals into high value-added products through catalytic strategy has a wide range of practical significance. Here, a palladium-catalyzed method for the direct and efficient dicarbonylation of amines with basic industrial feedstock ethylene to imide has been developed. Moderate to excellent yields of the desired imides can be produced from readily available amines in a straightforward manner.

Synthesis of sulfur heterocycles via domino metal-mediated reactions

Two methodologies to access S-heterocycles and mixed N,S-heterocycles via metal-mediated domino reactions are described. One involves a cyclocarbopalladation/cross-coupling domino process and leads to benzene-fused five- or six-membered sulfur heterocycles with a stereo defined tetrasubstituted exocyclic double bond. The other consists in a three-component domino reaction between 2-aminophenyl disulfide, copper cyanide, and an electrophile to access N-substituted 2-amino benzothiazoles. Preliminary results in the use of the second method to access N-substituted 2-imino benzothiazoles are also reported.

Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles

In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modifications on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property. The radioprotective activity has also been evaluated in mice. Some of these compounds could be good radioprotectors.