30041-95-3

Basic information

• Product Name: (4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER
• Synonyms: (4-cyanophenoxy)-aceticaciethylester;(4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER
• CAS NO: 30041-95-3
• Molecular Formula: C₁₁H₁₁NO₃
• Molecular Weight: 205.21
• Mol File: 30041-95-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 337°Cat760mmHg
• Flash Point: 146.9°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.000108mmHg at 25°C
• Refractive Index: 1.521
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER(30041-95-3)
• EPA Substance Registry System: (4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER(30041-95-3)

Safety Data

• Hazardous Substances Data: 30041-95-3(Hazardous Substances Data)

Usage

Description

(4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER, also known as ethyl (4-cyanophenoxy)acetate, is an ester compound that is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is derived from the combination of ethyl acetate and 4-cyanophenol, and is often used as a building block for the production of other chemicals. (4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER has a wide range of applications in the chemical industry, and its properties make it suitable for use in various chemical reactions and processes. Additionally, it has potential uses in the development of new drugs and advanced materials due to its unique chemical structure and reactivity.

Uses

Used in Pharmaceutical Industry:
(4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be a building block for the production of other chemicals.
Used in Agrochemical Industry:
(4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER is used as an intermediate in the synthesis of various agrochemicals for its ability to be a building block for the production of other chemicals.
Used in Chemical Industry:
(4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER is used in various chemical reactions and processes for its unique chemical structure and reactivity.
Used in Development of New Drugs:
(4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER is used in the development of new drugs due to its potential applications and unique chemical structure.
Used in Development of Advanced Materials:
(4-CYANOPHENOXY) ACETIC ACID ETHYL ESTER is used in the development of advanced materials due to its potential applications and unique chemical structure.

InChI:InChI=1/C11H11NO3/c1-2-14-11(13)8-15-10-5-3-9(7-12)4-6-10/h3-6H,2,8H2,1H3

Upstream product

• 1073-72-9 4-hydroxythioanisole 
• 557-21-1 zinc(II) cyanide 
• 15267-46-6 ethyl 2-(4-methylsulfanylphenoxy)acetate 
• 767-00-0 4-cyanophenol 
• 105-39-5 chloroacetic acid ethyl ester 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 56203-24-8 2-(4-Cyano-phenoxy)-N-[2-(2-hydroxy-2-phenyl-ethylamino)-ethyl]-acetamide 
• 57929-14-3 ethyl (4-ethoxy-carbonimidoyl-phenoxy)-acetate hydrochloride 
• 1272519-95-5 (Z)-methyl-2-(4-(5-(4-methoxybenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)phenoxy)acetate 
• 118641-15-9 C₁₃H₁₃NO₄ 
• 1308248-14-7 3-methyl-4-(4-cyanophenoxy)-1H-pyrazol-5(4H)-one 
• 207604-66-8 ethyl 2-(4-(amino-methyl)phenoxy)acetate 
• 1290056-31-3 ethyl 2-(4-((4-(((tert-butoxycarbonyl)amino)methyl)benzamido) methyl)phenoxy)acetate 
• 1290056-32-4 2-(4-((4-((Tert-butoxycarbonylamino)methyl)benzamido) methyl)phenoxy)acetic acid 
• 1290056-35-7 tert-butyl 4-(4-(2-((3R,4R)-3-(tert-butyldimethylsilyloxy)-4-hydroxypyrrolidin-1-yl)-2-oxoethoxy)benzylcarbamoyl)benzylcarbamate 
• 1290056-30-2 2-(4-((4-Cyanobenzamido) methyl)phenoxy)acetic acid 
• 1290053-51-8 (S)-4-(aminomethyl)-N-(4-(2-(3-hydroxy-4-oxopyrrolidin-1-yl)-2-oxoethoxy)benzyl)benzamide 
• 1290056-89-1 4-(aminomethyl)-N-(4-(2-((3aR,6aS)-2,2-dimethyldihydro-3aH-[1,3]dioxolo[4,5-c]pyrrol-5(4H)-yl)-2-oxoethoxy)benzyl)benzamide 
• 1290056-34-6 (S)-tert-butyl 4-(4-(2-(3-(tert-butyldimethylsilyloxy)-4-oxopyrrolidin-1-yl)-2-oxoethoxy)benzylcarbamoyl)benzylcarbamate 
• 1290053-54-1 4-(aminomethyl)-N-(4-(2-((3R,4R)-3,4-dihydroxypyrrolidin-1-yl)-2-oxoethoxy)benzyl)benzamide hydrochloride 

Relevant articles and documents

Nickel-Catalyzed Cyanation of Aryl Thioethers

A nickel-catalyzed cyanation of aryl thioethers using Zn(CN)2 as a cyanide source has been developed to access functionalized aryl nitriles. The ligand dcype (1,2-bis(dicyclohexylphosphino)ethane) in combination with the base KOAc (potassium acetate) is essential for achieving this transformation efficiently. This reaction involves both a C-S bond activation and a C-C bond formation. The scalability, low catalyst and reagents loadings, and high functional group tolerance have enabled both late-stage derivatization and polymer recycling, demonstrating the reaction's utility across organic chemistry.

Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs

Investigations regarding the chemistry and mechanism of action of 2-methyl-1,4-naphthoquinone (or menadione) derivatives revealed 3-phenoxymethyl menadiones as a novel anti-schistosomal chemical series. These newly synthesized compounds (1-7) and their di

Design and synthesis of heterocyclic cations for specific DNA recognition: From AT-rich to mixed-base-pair DNA sequences

The compounds synthesized in this research were designed with the goal of establishing a new paradigm for mixed-base-pair DNA sequence-specific recognition. The design scheme starts with a cell-permeable heterocyclic cation that binds to AT base pair sites in the DNA minor groove. Modifications were introduced in the original compound to include an H-bond accepting group to specifically recognize the G-NH that projects into the minor groove. Therefore, a series of heterocyclic cations substituted with an azabenzimidazole ring has been designed and synthesized for mixed-base-pair DNA recognition. The most successful compound, 12a, had an azabenzimidazole to recognize G and additional modifications for general minor groove interactions. It binds to the DNA site -AAAGTTT- more strongly than the -AAATTT- site without GC and indicates the design success. Structural modifications of 12a generally weakened binding. The interactions of the new compound with a variety of DNA sequences with and without GC base pairs were evaluated by thermal melting analysis, circular dichroism, fluorescence emission spectroscopy, surface plasmon resonance, and molecular modeling.