30163-20-3

Basic information

• Product Name: 2-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID
• Synonyms: DL-3-Br-Phe-OH;DL-2-Amino-3-(3-bromo-phenyl)-propionic acid;Phenylalanine, 3-broMo-;DL-3-Br-Phe-OH 3-BroMo-DL-Phenylalanine;3-Bromophenyl-DL-alanine;H-DL-Phe(3-Br);2-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID;3-BROMO-DL-PHENYLALANINE
• CAS NO: 30163-20-3
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.09
• Product Categories: Phenylalanine analogs and other aromatic alpha amino acids;a-amino
• Mol File: 30163-20-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 368.4 °C at 760 mmHg
• Flash Point: 176.6 °C
• Appearance: /Solid
• Density: 1.588 g/cm³
• Vapor Pressure: 4.46E-06mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.16±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID(30163-20-3)
• EPA Substance Registry System: 2-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID(30163-20-3)

Safety Data

• Hazardous Substances Data: 30163-20-3(Hazardous Substances Data)

Usage

General Description

2-Amino-3-(3-bromo-phenyl)-propionic acid is a chemical compound with the molecular formula C9H10BrNO2. It is a derivative of the amino acid phenylalanine, where the hydrogen atom at the 2-position is replaced with an amino group and the 3-position contains a bromo-phenyl group. 2-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its potential biological activities. It may act as a building block for the synthesis of various biologically active compounds and can also be used as a precursor in the production of other chemical compounds. The presence of the bromo-phenyl group also gives it unique properties that may be utilized in various chemical and industrial processes.

InChI:InChI=1/C9H10BrNO2/c10-7-3-1-2-6(4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1

Upstream product

• 14473-91-7 3-bromocinnamic acid 
• 823-78-9 meta-bromobenzyl bromide 
• 15017-44-4 diethyl (acetylamino)<(3-bromophenyl)methyl>propanedioate 

Downstream Products

• 1570043-29-6 ethyl 2-(1-(3-bromophenyl)-3-oxobutan-2-ylamino)-2-oxoacetate 
• 1570043-30-9 ethyl 4-(3-bromobenzyl)-5-methyloxazole-2-carboxylate 
• 1570043-31-0 4-(3-bromobenzyl)-5-methyloxazole-2-carboxylic acid 
• 1570043-27-4 5-(4-(3-bromobenzyl)-5-methyloxazol-2-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole 
• 1570043-34-3 ethyl 5-methyl-4-(3-(4-methylpiperazin-1-yl)benzyl)oxazole-2-carboxylate 

Relevant articles and documents

Bi-enzymatic Conversion of Cinnamic Acids to 2-Arylethylamines

The conversion of carboxylic acids, such as acrylic acids, to amines is a transformation that remains challenging in synthetic organic chemistry. Despite the ubiquity of similar moieties in natural metabolic pathways, biocatalytic routes seem to have been overlooked for this purpose. Herein we present the conception and optimisation of a two-enzyme system, allowing the synthesis of β-phenylethylamine derivatives from readily-available ring-substituted cinnamic acids. After characterisation of both parts of the reaction in a two-step approach, a set of conditions allowing the one-pot biotransformation was optimised. This combination of a reversible deaminating and irreversible decarboxylating enzyme, both specific for the amino acid intermediate in tandem, represents a general method by which new strategies for the conversion of carboxylic acids to amines could be designed.

Hydroxyethylene sulfones as a new scaffold to address aspartic proteases: Design, synthesis, and structural characterization

Hydroxyethylene sulfones were developed as novel scaffolds against aspartyl proteases. A diastereoselective synthesis has been established to introduce the required side chain decoration with desired stereochemistry. Depending on the substitution of the h