30166-88-2

Basic information

• Product Name: (E)-2-(4-methylphenyl)ethenyl phenyl sulfone
• CAS NO: 30166-88-2
• Molecular Formula: C₁₅H₁₄O₂S
• Molecular Weight: 258.3355
• Mol File: 30166-88-2.mol
• Article Data: 56

Chemical Properties

• Boiling Point: 450.7°C at 760 mmHg
• Flash Point: 281.1°C
• Density: 1.194g/cm³
• Vapor Pressure: 6.89E-08mmHg at 25°C
• Refractive Index: 1.6
• CAS DataBase Reference: (E)-2-(4-methylphenyl)ethenyl phenyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-methylphenyl)ethenyl phenyl sulfone(30166-88-2)
• EPA Substance Registry System: (E)-2-(4-methylphenyl)ethenyl phenyl sulfone(30166-88-2)

Safety Data

• Hazardous Substances Data: 30166-88-2(Hazardous Substances Data)

Usage

Description

(E)-2-(4-methylphenyl)ethenyl phenyl sulfone is a chemical compound with the molecular formula C14H12O2S. It is a sulfone compound that consists of a phenyl group attached to a sulfone group and a methylphenyl group attached to an ethenyl group. (E)-2-(4-methylphenyl)ethenyl phenyl sulfone is known for its unique chemical properties and is often utilized in various organic synthesis processes.

Uses

Used in Pharmaceutical Industry:
(E)-2-(4-methylphenyl)ethenyl phenyl sulfone is used as a reagent for the synthesis of various pharmaceuticals. Its unique structure allows it to participate in organic synthesis processes, contributing to the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical industry, (E)-2-(4-methylphenyl)ethenyl phenyl sulfone is used as a reactant in the production of agrochemicals. Its involvement in organic synthesis aids in the creation of compounds that can be used in the development of pesticides, fertilizers, and other agricultural products.
Used in Organic Synthesis:
(E)-2-(4-methylphenyl)ethenyl phenyl sulfone is used as a reactant in the Heck reaction, a palladium-catalyzed coupling reaction for the synthesis of carbon-carbon bonds. This reaction is crucial in the formation of complex organic molecules, which are essential in various chemical and pharmaceutical applications.
Used in Materials Science:
Due to its unique chemical properties, (E)-2-(4-methylphenyl)ethenyl phenyl sulfone may have potential applications in materials science. It could be utilized in the development of new materials with specific properties, such as improved strength, durability, or chemical resistance, depending on the requirements of various industrial processes.

Upstream product

• 62761-90-4 α,α-bis(trimethylsilyl)methylphenyl sulfide 
• 104-87-0 4-methyl-benzaldehyde 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 98-09-9 benzenesulfonyl chloride 
• 873-55-2 sodium benzenesulfonate 
• 73839-45-9 (E)-trimethyl[2-(4-methylphenyl)ethenyl]silane 
• 3959-23-7 benzenesulfonylacetic acid 
• 5535-48-8 PVS 
• 459-44-9 4-methylbenzenediazonium tetrafluoroborate 
• 82721-80-0 1-methyl-4-((phenylsulfonyl)ethynyl)benzene 
• 5720-05-8 4-methylphenylboronic acid 
• 60655-80-3 (E)-4-methylstyrenyl bromide 
• 56069-39-7 diethyl phenylsulfonylmethylphosphonate 
• 766-97-2 4-n-methylphenylacetylene 

Downstream Products

• 21309-11-5 1-((1S,2R)-2-Benzenesulfonyl-cyclopropyl)-4-methyl-benzene 
• 1097725-22-8 methyl 4-phenylsulfonyl-3-(4-methylphenyl)butyrate 
• 125951-08-8 (Z)-1-methyl-4-[2-(phenylsulfanyl)ethenyl]benzene 
• 125951-09-9 (E)-1-methyl-4-[2-(phenylsulfanyl)ethenyl]benzene 
• 1202166-97-9 2-[(E)-2-(4-methylphenyl)ethenyl]tetrahydrofuran 

Relevant articles and documents

Controlled Synthesis of β-Keto Sulfones and Vinyl Sulfones under Electrochemical Oxidation

Selective sulfonylation and oxosulfonylation of alkenes with sulfinates have been developed via anodic oxidation in an undivided cell. The novel electrosynthetic method provided β-keto sulfones and vinyl sulfones with good to excellent yields in the absence of any transition metal catalyst and oxidants. Mechanism studies show that two different pathways involved in these two transformations.

Visible-Light-Induced Three-Component Intermolecular Trifluoromethyl-Alkenylation Reactions of Unactivated Alkenes

Herein, we describe a practical protocol for efficient, mild, visible-light-induced three-component intermolecular trifluoromethyl-alkenylation reactions of unactivated alkenes. The protocol has good functional group tolerance and a broad substrate scope. Using this protocol, we not only introduced a trifluoromethyl group into alkenes but also converted unactivated alkenes to styrene-based activated alkenes, in addition to accomplishing late-stage functionalization of pharmaceutical intermediates. (Figure presented.).

Intermolecular [2 + 2] Photocycloaddition of α,β-Unsaturated Sulfones: Catalyst-Free Reaction and Catalytic Variants

2-Aryl-1-sulfonyl-substituted cyclobutanes were prepared in an intermolecular [2 + 2] photocycloaddition from various α,β-unsaturated sulfones and olefins upon irradiation at λ = 300 nm (26 examples, 60-99% yield). Lewis acids catalyzed the [2 + 2] photocycloaddition of 2-benzimidazolyl styryl sulfones. At short wavelengths, the latter substrates underwent C-S bond cleavage but AlBr3 (5 mol %) allowed for an intermolecular reaction with 2,3-dimethyl-2-butene at longer wavelengths. A chiral-at-metal Lewis acid (2 mol %) facilitated an enantioselective reaction (up to 77% ee).