301699-39-8 Usage
Description
3,5-Dimethyl-4-methoxyphenylboronic acid is an organic compound with the molecular formula C9H13BO3. It is a boronic acid derivative featuring a phenyl ring with two methyl groups at the 3rd and 5th positions and a methoxy group at the 4th position. 3,5-Dimethyl-4-methoxyphenylboronic acid is known for its reactivity and utility in various chemical reactions and synthesis processes.
Uses
Used in Pharmaceutical Industry:
3,5-Dimethyl-4-methoxyphenylboronic acid is used as a reactant for the preparation of biologically and pharmacologically active molecules. Its unique structure allows it to be a versatile building block in the synthesis of various drugs and pharmaceutical compounds.
Used in Chemical Synthesis:
3,5-Dimethyl-4-methoxyphenylboronic acid is used as a reactant in Suzuki and Stille cross-coupling reactions. These reactions are widely employed in the formation of carbon-carbon bonds, which are crucial in the synthesis of complex organic molecules, including those with potential applications in materials science and pharmaceuticals.
Used in Organic Chemistry:
3,5-Dimethyl-4-methoxyphenylboronic acid is also used in Mizoroki-Heck arylation, a type of carbon-carbon bond-forming reaction that is useful for the synthesis of various organic compounds, particularly those with aromatic rings.
Used in Baeyer-Villiger Oxidation:
3,5-Dimethyl-4-methoxyphenylboronic acid can be utilized in Baeyer-Villiger oxidation, a reaction that involves the conversion of ketones to esters or lactones. This reaction is essential in the synthesis of various organic compounds, including pharmaceuticals and fragrances.
Used in Asymmetric Conjugate Addition Reactions:
Lastly, 3,5-Dimethyl-4-methoxyphenylboronic acid is used in rhodium-catalyzed asymmetric conjugate addition reactions. These reactions are vital in the synthesis of enantiomerically pure compounds, which are crucial in the development of chiral drugs and other biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 301699-39-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,1,6,9 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 301699-39:
(8*3)+(7*0)+(6*1)+(5*6)+(4*9)+(3*9)+(2*3)+(1*9)=138
138 % 10 = 8
So 301699-39-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H13BO3/c1-6-4-8(10(11)12)5-7(2)9(6)13-3/h4-5,11-12H,1-3H3
301699-39-8Relevant articles and documents
Formation of hetero-boroxines: Dynamic combinatorial libraries generated through trimerization of pairs of arylboronic acids
Tokunaga, Yuji,Ueno, Hiroki,Shimomura, Youji
, p. 219 - 223 (2008/09/17)
Condensation of pairs of arylboronic acids provided homo- and hetero-boroxines in solution as evidenced from NMR spectra, and those boroxines were detected in the gas phase by GC-MS spectrometry. Equilibrium constants for the formation of these boroxines in solution were obtained through integration of pertinent signals in the NMR spectra of the mixtures ofboronic acids.
