30203-84-0 Usage
Description
1-(4-Bromobenzyl)-4-chlorobenzene, also known as BCB, is a chemical compound that features a benzene ring with a bromine atom and a chlorine atom attached at different positions. This structure endows BCB with unique reactivity and makes it a valuable intermediate in the synthesis of various organic compounds.
Uses
Used in Organic Synthesis:
1-(4-Bromobenzyl)-4-chlorobenzene is used as a versatile intermediate for the production of a wide range of organic compounds. Its ability to react with various reagents allows for the formation of other functionalized benzene derivatives, which are essential in creating new materials and chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(4-Bromobenzyl)-4-chlorobenzene is used as a building block in the design and synthesis of potential drug candidates. Its unique structure and reactivity contribute to the development of new pharmaceuticals with specific therapeutic properties.
Used in Agrochemicals:
BCB also plays a role in the agrochemical industry, where it is utilized in the development of new compounds with applications in agriculture, such as pesticides and herbicides.
Used in the Development of New Materials:
The structure and reactivity of 1-(4-Bromobenzyl)-4-chlorobenzene make it an important reagent in the creation of new materials with potential applications in various industries, including electronics, coatings, and plastics.
Check Digit Verification of cas no
The CAS Registry Mumber 30203-84-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,2,0 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 30203-84:
(7*3)+(6*0)+(5*2)+(4*0)+(3*3)+(2*8)+(1*4)=60
60 % 10 = 0
So 30203-84-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H10BrCl/c14-12-5-1-10(2-6-12)9-11-3-7-13(15)8-4-11/h1-8H,9H2
30203-84-0Relevant articles and documents
Metal-Free C-O Bond Functionalization: Catalytic Intramolecular and Intermolecular Benzylation of Arenes
Bering, Luis,Jeyakumar, Kirujan,Antonchick, Andrey P.
supporting information, p. 3911 - 3914 (2018/07/22)
A catalytic, metal-free intramolecular rearrangement of benzyl phenyl ethers using nitrosonium salt as a catalyst is described. The optimized reaction conditions enabled a catalytic and metal-free Friedel-Crafts alkylation reaction with benzylic alcohols, producing water as the stoichiometric byproduct. A comprehensive scope (>50 examples) for both approaches and application in drug synthesis were demonstrated. Mechanistic studies suggest a Lewis acid-based mechanism for the metal-free Friedel-Crafts reaction.
Investigating the Reactivity of 1,4-Anthracene-Incorporated Cycloparaphenylene
Li, Penghao,Wong, Bryan M.,Zakharov, Lev N.,Jasti, Ramesh
supporting information, p. 1574 - 1577 (2016/05/02)
Cycloparaphenylenes (CPPs) and their derivatives are unique conjugated macrocycles with novel optoelectronic and host-guest properties. A better understanding of their reactivity is essential for creating new functional materials utilizing these strained
Flow chemistry as a discovery tool to access sp2-sp3 cross-coupling reactions via diazo compounds
Tran, Duc N.,Battilocchio, Claudio,Lou, Shing-Bong,Hawkins, Joel M.,Ley, Steven V.
, p. 1120 - 1125 (2015/03/04)
The work takes advantage of an important feature of flow chemistry, whereby the generation of a transient species (or reactive intermediate) can be followed by a transfer step into another chemical environment, before the intermediate is reacted with a coupling partner. This concept is successfully applied to achieve a room temperature sp2-sp3 cross coupling of boronic acids with diazo compounds, these latter species being generated from hydrazones under flow conditions using MnO2 as the oxidant.