30291-41-9

Basic information

• Product Name: 4-methyloxazolidine-2,5-dione
• Synonyms: 2,5-Oxazolidinedione,4-methyl-(6CI,7CI,9CI);4-Methyl-2,5-oxazolidinedione;Einecs 250-114-1;DL-Alanine-N-carboxy anhydride;L-alanine N-carboxyanhydride;-methyloxazolidine-2,5-dione
• CAS NO: 30291-41-9
• Molecular Formula: C4H5NO3
• Molecular Weight: 115.0874
• EINECS: 250-114-1
• Product Categories: GLYCINESCAFFOLD
• Mol File: 30291-41-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.296g/cm³
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 4-methyloxazolidine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyloxazolidine-2,5-dione(30291-41-9)
• EPA Substance Registry System: 4-methyloxazolidine-2,5-dione(30291-41-9)

Safety Data

• Hazardous Substances Data: 30291-41-9(Hazardous Substances Data)

Usage

Description

4-methyloxazolidine-2,5-dione is a heterocyclic organic compound with the molecular formula C5H7NO3. It is a five-membered ring containing an oxygen atom, a nitrogen atom, and a methyl group. 4-methyloxazolidine-2,5-dione is known for its potential applications in various industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
4-methyloxazolidine-2,5-dione is used as an intermediate in the synthesis of various pharmaceutical compounds. Its ability to form stable structures and its reactivity make it a valuable building block for the development of new drugs.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-methyloxazolidine-2,5-dione is used as a versatile reagent for the production of different organic compounds. Its unique structure allows for various chemical reactions, making it a useful component in the synthesis of a wide range of products.
Used in Research and Development:
4-methyloxazolidine-2,5-dione is also utilized in research and development for the study of its chemical properties and potential applications. Its unique structure and reactivity make it an interesting subject for scientific investigation, which could lead to the discovery of new compounds and applications.
Used in Polymer Science:
In polymer science, 4-methyloxazolidine-2,5-dione can be used as a monomer for the synthesis of polymers with specific properties. Its incorporation into polymer chains can result in materials with unique characteristics, such as improved stability or enhanced reactivity.
Used in Cosmetics Industry:
4-methyloxazolidine-2,5-dione may also find applications in the cosmetics industry, where it can be used as an ingredient in the formulation of various cosmetic products. Its unique properties could contribute to the development of innovative products with improved performance and efficacy.

InChI:InChI=1/C4H5NO3/c1-2-3(6)8-4(7)5-2/h2H,1H3,(H,5,7)

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 56-41-7 L-alanine 
• 15761-38-3 L-N-Boc-Ala 
• 302-72-7 rac-Ala-OH 
• 77340-50-2 N-carbamoyl-DL-alanine 
• 75-44-5 phosgene 
• 2899-44-7 N,O-bis(trimethylsilyl)-α-alanine 
• 34653-64-0 N-ethoxycarbonyl-DL-alanine trimethylsilanyl ester 
• 4132-86-9 N-benzyloxycarbonylalanine 
• 3744-87-4 Boc-(R)-Ala 
• 26607-51-2 N-benzyloxycarbonyl-D-alanine 
• 338-69-2 D-Alanine 

Downstream Products

• 5265-18-9 (+/-)-cathinone 
• 129288-48-8 (R)-benzyl 4-methyl-2,5-dioxooxazolidine-3-carboxylate 
• 2508-25-0 DL-alanine hydroxamic acid 
• 34582-44-0 5-Cyclohexyl-2-methylhydantoinsaeure 
• 86211-51-0 D,L-alanine cyclohexylamide 
• 34582-46-2 2-(3-Benzyl-ureido)-propionic acid 
• 124491-96-9 (RS)-alanine N,N-dimethylamide 

Relevant articles and documents

Capsidone artificial hapten, artificial antigen and preparation method and application thereof

The invention relates to the field of cathinone artificial antigen structures, and particularly relates to a cathinone artificial antigen, an artificial antigen as well as a preparation method and application thereof. The cathinone artificial antigen is characterized in that a molecular structural formula of the cathinone artificial antigen is shown as follows: the formula (1) is shown in the description. According to the cathinone artificial antigen provided by the invention, a connecting arm is introduced onto a site N of cathinone, and the connecting arm is introduced onto the decoration site so that a characteristic structure of the cathinone is kept to a maximum extent; moreover, the cathinone artificial antigen has an active group coupled with carrier protein and can be used as an antigen determinant group. Compared with an annular connecting arm, the connecting arm adopted by the invention is chain-shaped, an identification degree of T cells to the connecting arm can be reducedas much as possible during immunization, so that an antibody obtained by immunization has higher specificity and affinity to the cathinone.

Novel derivatives of substituted 6-fluorobenzothiazole diamides: synthesis, antifungal activity and cytotoxicity

A new series of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-substituted phenyl diamides were synthesized in vitro as potential antifungal agents. Chemical structures of the synthesised compounds were substantiated by IR, 1H, 13C, 19F nuclear magnetic resonance spectra, high resolution mass spectrometry, elemental analysis and also by X-ray diffraction. In addition, the cytotoxicity of the most active compounds was investigated against cancer cell line (Jurkat) and one type of normal lung fibroblast cells (MRC-5) by (2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide) tetrazolium salt reduction assay, propidium iodide flow cytometry assay and xCELLigence system allowing a label-free assessment of the cells proliferation. Compounds indicated as 11e, 11g, 11j, 11n and 11o, were the best of the series, showing minimum inhibitory concentration values of 6.25–50 μg/mL against pathogenic strains Candida albicans HE 169, Candida tropicalis 31/HK and Candida parapsilosis p69. Moreover compounds 11e, 11g, 11j and 11o did not show any cytotoxic effect against human Jurkat and MRC-5 cells.

Synthesis of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-substituted phenyl ureas and their inhibition activity to acetylcholinesterase and butyrylcholinesterase

A series of novel 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3- substituted phenyl ureas were synthesized by the condensation of (1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethanamine with substituted phenyl isocyanates under mild conditions. Their structures were confirmed 1H, 13C, and 19F NMR spectra, and elemental analyses. The optical activities were confirmed by optical rotation measurements. The inhibition activity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2- yl)ethyl]-3-substituted phenyl ureas to acetylcholinesterase (ACHE) and butyrylcholinesterase (BCHE) was also tested. Preliminary bioassay indicated that the target ureas displayed excellent acetylcholinesterase and butyrylcholinesterase inhibition activity.