3030-45-3

Basic information

• Product Name: bis[2-(dimethylamino)ethyl] carbonate
• Synonyms: Bis(2-(dimethylamino)ethyl) carbonate; Bis[2-(dimethylamino)ethyl] carbonate; Carbonic acid, bis(2-(dimethylamino)ethyl) ester; carbonic acid, bis[2-(dimethylamino)ethyl] ester
• CAS NO: 3030-45-3
• Molecular Formula: C₉H₂₀N₂O₃
• Molecular Weight: 204.2667
• Mol File: 3030-45-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 240.1°C at 760 mmHg
• Flash Point: 99°C
• Density: 1.014g/cm³
• Vapor Pressure: 0.0387mmHg at 25°C
• Refractive Index: 1.455
• CAS DataBase Reference: bis[2-(dimethylamino)ethyl] carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: bis[2-(dimethylamino)ethyl] carbonate(3030-45-3)
• EPA Substance Registry System: bis[2-(dimethylamino)ethyl] carbonate(3030-45-3)

Safety Data

• Hazardous Substances Data: 3030-45-3(Hazardous Substances Data)

Upstream product

• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 105-58-8 Diethyl carbonate 
• 75-44-5 phosgene 
• 616-38-6 carbonic acid dimethyl ester 

Relevant articles and documents

Synthesis of dimethyl carbonate (DMC) based biodegradable nitrogen mustard ionic carbonate (NMIC) nanoparticles

Chitosan-nitrogen mustard ionic carbonate nanoparticles (C-NMIC-Nps) were fabricated for the first time by an ionotropic gelation method. The preparation of C-NMIC-Nps involved four steps. In the first step, green reagent dimethyl carbonate (DMC) reacted with 2-dimethylethanolamine (DMEA) to form bis-(2-dimethyl amino-ethyl)carbonate (DAEC). In the second step, DAEC underwent cationization with (1-chloro-2,3 epoxy)propane to form NMIC with a stable carbonate backbone having a greater number of sorption sites. Later, NMIC was successfully cross linked with chitosan to form C-NMIC, which was later on used to form C-NMIC nanoparticles (C-NMIC-Nps) by ionotropic gelation. The chemical structure of NMIC and C-NMIC was identified by proton nuclear magnetic resonance (1H-NMR), 13C nuclear magnetic resonance (13C-NMR) spectroscopy and elemental analysis. The spherical shaped, smooth and uniform distribution of the C-NMIC-Nps was observed by scanning electron microscopy (SEM) and high resolution transmission electron microscopy (HRTEM). The average particle size distribution of the C-NMIC-Nps was found to be 14.4 ± 3.1 nm as observed using a particle size analyzer. The functional groups of DAEC, NMIC and C-NMIC were identified by Fourier transform infrared spectroscopy (FTIR). The conversion of the crystalline nature of chitosan to the amorphous state in C-NMIC-Nps was studied by X-ray diffraction (XRD). The thermal stability of the C-NMIC-Nps was confirmed by thermo gravimetric analysis (TGA). The good cell viability of C-NMIC-Nps was assessed by in vitro MTT assay using VERO cell lines. Overall, the results suggested that C-NMIC-Nps had been prepared successfully. The prepared C-NMIC-Nps will act as a nano carrier of growth factors for wound healing application.

Process for the preparation of tertiary aminocarbonates and aminoethers

The invention relates to processes for producing di-(tertiary aminoalkyl) carbonate including the step of reacting a tertiary alkanolamine with methyl alkyl carbonate in the presence of a transesterification catalyst to form tertiary aminoalkyl alkyl carbonate, wherein some of the tertiary alkanolamine reacts with the tertiary aminoalkyl alkyl carbonate to form di-(tertiary aminoalkyl) carbonate. The invention also relates to processes for producing di-(tertiary aminoalkyl) carbonate including the steps of (i) reacting dimethyl carbonate with an alcohol in the presence of a transesterification catalyst to form a methyl alkyl carbonate, and (ii) reacting a tertiary alkanolamine with the methyl alkyl carbonate formed in step i) in the presence of a transesterification catalyst to form tertiary aminoalkyl alkyl carbonate, wherein some of the tertiary alkanolamine reacts with the tertiary aminoalkyl alkyl carbonate to form di-(tertiary aminoalkyl) carbonate.