30311-60-5

Basic information

• Product Name: quercetin-3-O-D-glucoside-7-O-D-glucoside
• CAS NO: 30311-60-5
• Molecular Weight: 626.525
• Mol File: 30311-60-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: quercetin-3-O-D-glucoside-7-O-D-glucoside(CAS DataBase Reference)
• NIST Chemistry Reference: quercetin-3-O-D-glucoside-7-O-D-glucoside(30311-60-5)
• EPA Substance Registry System: quercetin-3-O-D-glucoside-7-O-D-glucoside(30311-60-5)

Safety Data

• Hazardous Substances Data: 30311-60-5(Hazardous Substances Data)

Upstream product

• 117-39-5 quercetol 
• 153-18-4 rutin 
• 116973-12-7 5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-3-hydroxy-4H-chromen-4-one 
• 1332833-26-7 C₅₇H₅₂O₁₆ 
• 1332833-27-8 5,7-bisbenzyloxy-2-(3,4-bisbenzyloxyphenyl)-3-(β-D-glucopyranosyloxy)-4H-chromen-4-one 
• 482-35-9 isoquercetin 
• 1542609-36-8 C₃₅H₃₈O₂₁ 
• 6919-96-6 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 133-89-1 UDP-glucose 

Downstream Products

• 50-99-7 D-glucose 
• 117-39-5 quercetol 

Relevant articles and documents

Cloning and functional characterisation of two regioselective flavonoid glucosyltransferases from Beta vulgaris

Two full-length cDNAs encoding flavonoid-specific glucosyltransferases, UGT73A4 and UGT71F1, were isolated from a cDNA library of Beta vulgaris (Amaranthaceae) cell suspension cultures. They displayed high identity to position-specific betanidin and flavonoid glucosyltransferases from Dorotheanthus bellidiformis (Aizoaceae) and to enzymes with similar substrate specificities from various plant families. The open reading frame of the sequences encode proteins of 476 (UGT73A4) and 492 (UGT71F1) amino acids with calculated molecular masses of 54.07 kDa and 54.39 kDa, and isoelectric points of 5.8 and 5.6, respectively. Both enzymes were functionally expressed in Escherichia coli as His- and GST-tagged proteins, respectively. They exhibited a broad substrate specificity, but a distinct regioselectivity, glucosylating a variety of flavonols, flavones, flavanones, and coumarins. UGT73A4 showed a preference for the 4′- and 7-OH position in the flavonoids, whereas UGT71F1 preferentially glucosylated the 3- or the 7-OH position. Glucosylation of betanidin, the aglycone of the major betacyanin, betanin, in B. vulgaris was also observed to a low extent by both enzymes. Several O-glycosylated vitexin derivatives isolated from leaves of young B. vulgaris plants and rutin obtained from B. vulgaris tissue culture are discussed as potential endogenous products of UGT73A4 and UGT71F1. The results are analyzed with regard to evolution and specificity of plant natural product glucosyltransferases.

Glucosylation of Quercetin by a Cell Suspension Culture of Vitis sp.

A cell suspension culture of a Vitis hybrid converted quercetin to six glucosides.Their structures were identified as quercetin 3-O-β-D-glucopyranoside, quercetin 3,4'-di-O-β-D-glucopyranoside, quercetin 3,7-di-O-β-D-glucopyranoside, isorhamnetin 3-O-β-D-glucopyranoside, isorhamnetin 3,4'-di-O-β-D-glucopyranoside, and isorhamnetin 3,7-di-O-β-D-glucopyranoside by UV, FD-MS, 1H-NMR, 13C-NMR spectroscopy and TLC analysis.The course of conversion was also investigated and it was shown that quercetin 3-O-glucoside reached the maximum yield of 31 percent in 24 hr and then gradually disappeared accompanied by the production of quercetin 3,4'- and 3,7-di-O-glucosides.Although the same rise and fall relationship was observed between isorhamnetin 3-O-glucoside and isorhamnetin 3,4'- or 3,7-di-O-glucoside, their conversion ratios were much lower than those of quercetin glucosides.